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European Heart Journal Advance Access originally published online on July 28, 2008
European Heart Journal 2008 29(17):2064-2066; doi:10.1093/eurheartj/ehn342
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Late drug-eluting stent thrombosis in unprotected left main coronary artery lesions—sometimes possible, but rarely definite or probable

Hussam Hamdalla and David J. Moliterno*

Gill Heart Institute and Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY 40536, USA

* Corresponding author. Tel: +1 859 323 5843, Fax: +1 859 257 3537, Email: Moliterno@uky.edu

This editorial refers to ‘Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry’{dagger} by A. Chieffo et al., on page 2108

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 150 words of the full text of this article appear below.

Beyond relieving angina, revascularization strategies for coronary artery disease (CAD) have focused on the subsequent occurrence of death, myocardial infarction, repeat revascularization, and, more recently, stent thrombosis. Numerous trials comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) have shown the long-term rates of death and myocardial infarction to be similar between these strategies, largely independently of the extent and location of CAD.1,2 The main outcome gap between percutaneous and surgical approaches has been the higher rate of repeat revascularization procedures for those initially undergoing PCI. At 5-year follow-up in the Bypass Angioplasty Revascularization Investigation (BARI) trial,1 54% of patients initially undergoing multivessel balloon angioplasty required a repeat procedure vs. 8% among those assigned to bypass surgery. With the introduction of bare-metal stents . . . [Full Text of this Article]


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Related articles in EHJ:

Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry
Alaide Chieffo, Seung-Jung Park, Emanuele Meliga, Imad Sheiban, Michael S. Lee, Azeem Latib, Young-Hak Kim, Marco Valgimigli, Dario Sillano, Valeria Magni, Giuseppe Biondi-Zoccai, Matteo Montorfano, Flavio Airoldi, Renata Rogacka, Mauro Carlino, Iassen Michev, Cheol-Whan Lee, Myeong-Ki Hong, Seong-Wook Park, Claudio Moretti, Erminio Bonizzoni, Giuseppe M. Sangiorgi, Jonathan Tobis, Patrick W. Serruys, and Antonio Colombo
EHJ 2008 29: 2108-2115. [Abstract] [FREE Full Text]