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European Heart Journal Advance Access originally published online on August 27, 2008
European Heart Journal 2008 29(19):2323-2324; doi:10.1093/eurheartj/ehn392
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Identifying patterns of atherosclerotic disease manifestation with coronary computed tomography. Impact on clinical management and outcome?

Paul Schoenhagen* and E. Murat Tuzcu

The Cleveland Clinic, Imaging Institute and Heart & Vascular Institute, 9500 Euclid Ave., Cleveland, OH 44195, USA

* Corresponding author. Tel: +1 216 445-7579, Fax: +1 216 445-6855, Email: schoenp1@ccf.org

This editorial refers to ‘Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis’{dagger} by G. Pundziute et al., on page 2373

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

Since its introduction as a tool for non-invasive coronary imaging, computed tomographic angiography (CTA) has undergone significant clinical validation. Its feasibility and diagnostic performance for the assessment of luminal stenosis have been evaluated against conventional angiography.1,2 In multiple comparative studies, it has been demonstrated that significant luminal stenosis can be excluded with high negative predictive value. The positive predictive value for the detection of stenotic lesions is reduced by stenosis overestimation due to artefact associated with advanced, calcified atherosclerotic lesions. At the same . . . [Full Text of this Article]


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Related articles in EHJ:

Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis
Gabija Pundziute, Joanne D. Schuijf, J. Wouter Jukema, Isabel Decramer, Giovanna Sarno, Piet K. Vanhoenacker, Eric Boersma, Johan H.C. Reiber, Martin J. Schalij, William Wijns, and Jeroen J. Bax
EHJ 2008 29: 2373-2381. [Abstract] [FREE Full Text]