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European Heart Journal Advance Access originally published online on January 17, 2008
European Heart Journal 2008 29(3):290-292; doi:10.1093/eurheartj/ehm593
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org.

Neurohormones in valvular heart disease: what can they tell us?

Helmut Baumgartner*

Adult Congenital and Valvular Heart Disease Center (EMAH-Zentrum), University Hospital Muenster, Albert-Schweitzer-Str. 33, D-48149 Muenster, Germany

* Corresponding author. Tel: +49 251 83 46110, Fax +49 51 46109. Email: helmut.baumgartner@ukmuenster.de

This editorial refers to ‘Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation’ by A.J. Kerr et al.,{dagger} on page 363

Footnotes

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 150 words of the full text of this article appear below.

Management of valvular heart disease has dramatically changed over the last decades. Although valve surgery has been shown to be capable of reducing or even eliminating symptoms, it has also been recognized that outcome is unsatisfactory when intervention occurs too late. Already irreversible damage of the myocardium and/or pulmonary vasculature causes ongoing morbidity and increased mortality. Thus, long-term preservation of ventricular function has become one of the major goals in the management of valvular heart disease.1 With respect to this, early surgery has been proposed to protect the myocardium from irreversible damage. However, surgery itself bears some risk and, particularly when prosthetic heart valves are used, long-term morbidity caused by surgery itself must be taken into account. Thus, risk must be carefully weighed against benefit, . . . [Full Text of this Article]


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Related articles in EHJ:

Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation
Andrew J. Kerr, O. Christopher Raffel, Gillian A. Whalley, Irene Zeng, and Ralph A. Stewart
EHJ 2008 29: 363-370. [Abstract] [Full Text]