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European Heart Journal 2008 29(4):434-435; doi:10.1093/eurheartj/ehn030
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

MR perfusion imaging. What will be its impact for detection of coronary disease in the future?

Bernhard L. Gerber*

Division of Cardiology, Department of Cardiovasular Diseases, Cliniques Universitaires St. Luc UCL, Av Hippocrate 10/2806, B-1200 Woluwe St Lambert, Belgium

* Corresponding author. Tel: +32 2 7642803, Fax: +32 2 7642811, Email: Bernhard.gerber@clin.ucl.ac.be

This editorial refers to ‘MR-IMPACT: comparison of perfusion-cardiac magnetic resonance with single-photon emission computed tomography for the detection of coronary artery disease in a multicentre, multivendor, randomized trial’ by J. Schwitter et al.,{dagger} on page 480

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

Revealing stress-induced myocardial ischaemia is a well-established method for evaluating the presence and pathophysiological severity of coronary artery disease. In clinical practice, exercise or pharmacological stress nuclear imaging are the most widely used techniques for this purpose. According to two meta-analyses, exercise1 and dipyridamole and adenosine stress2 single-photon emission computed tomography (SPECT) have respectively 87, 89, and 90% sensitivity and 64, 65, and 75% specificity for detection of angiographically significant coronary artery disease. Detection of myocardial ischaemia by nuclear imaging also has prognostic value for predicting cardiac events3,4 such as death or myocardial infarction. Nevertheless, nuclear imaging has several significant limitations: indeed the test is . . . [Full Text of this Article]


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Related articles in EHJ:

MR-IMPACT: comparison of perfusion-cardiac magnetic resonance with single-photon emission computed tomography for the detection of coronary artery disease in a multicentre, multivendor, randomized trial
Juerg Schwitter, Christian M. Wacker, Albert C. van Rossum, Massimo Lombardi, Nidal Al-Saadi, Hakan Ahlstrom, Thorsten Dill, Henrik B.W. Larsson, Scott D. Flamm, Moritz Marquardt, and Lars Johansson
EHJ 2008 29: 480-489. [Abstract] [FREE Full Text]