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European Heart Journal Advance Access originally published online on April 17, 2009
European Heart Journal 2009 30(10):1167-1168; doi:10.1093/eurheartj/ehp167
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Metabolic syndrome and postoperative atrial fibrillation (POAF)

David S.H. Bell1,* and James H. O'Keefe2

1 University of Alabama Medical School-Birmingham, AL, USA
2 Mid America Heart Institute and University of Missouri-Kansas City, USA

* Corresponding author. Tel: +1 205 933 2667, Fax: +1 205 933 2693, Email: dshbell@yahoo.com

This editorial refers to ‘Middle-aged men with increased waist circumference and elevated C-reactive protein level are at higher risk for postoperative atrial fibrillation following coronary artery bypass grafting surgery’{dagger}, by N. Girerd et al., on page 1270

The first 10% of the full text of this article appears below.

Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice, and the lifetime risk of developing AF is 25%.1 Even in the absence of structural heart disease AF is extremely common and is associated with an increased risk of stroke, heart failure, and death. Risk factors for AF are age, sleep apnoea, valvular heart disease, hypertension, obesity, male gender, and type 2 diabetes.1

The key lesion in developing AF is dilatation of the left atrium, for which there are multiple causes in the type 2 diabetic patient.2 Approximately 75% of type 2 diabetic subjects are hypertensive. For every molecule of glucose that is filtered and reabsorbed in the kidney, one molecule of sodium is also absorbed. High insulin and glucose levels lead to salt and water retention, activation of . . . [Full Text of this Article]


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Related articles in EHJ:

Middle-aged men with increased waist circumference and elevated C-reactive protein level are at higher risk for postoperative atrial fibrillation following coronary artery bypass grafting surgery
Nicolas Girerd, Philippe Pibarot, Dominique Fournier, Pascal Daleau, Pierre Voisine, Gilles O'Hara, Jean-Pierre Després, and Patrick Mathieu
EHJ 2009 30: 1270-1278. [Abstract] [Full Text]