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European Heart Journal Advance Access originally published online on April 24, 2009
European Heart Journal 2009 30(11):1301-1304; doi:10.1093/eurheartj/ehp168
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

Dysglycaemia, cardiovascular outcome and treatment. Is the jury still out?

Malgorzata Bartnik1 and Francesco Cosentino2,*

1 Department of Medicine, Skaraborg Hospital, Kärnsjukhuset Skövde, Sweden
2 Division of Cardiology, 2nd Faculty of Medicine, University ‘La Sapienza’, Rome, Italy

Corresponding author. Tel: +39 06 33775561, Fax: +39 06 33775061, Email: f_cosentino@hotmail.com

This editorial refers to ‘Glycaemic control in newly diagnosed diabetes patients and mortality from ischaemic heart disease: 20-year follow-up of the HUNT Study in Norway’{dagger}, by A.C. Dale et al., on page 1372

The first 150 words of the full text of this article appear below.

Dale and co-workers have reported on the influence of glycaemic control on long-term mortality from ischaemic heart disease (IHD) in patients with asymptomatic newly detected diabetes mellitus participating in a population-wide health survey in Norway.1 The annual measurements of glycated haemoglobin A1c (HbA1c) in subjects with newly diagnosed diabetes during the 10 years following recruitment constitute a strength of this study allowing assessment of how risk may vary according to glycaemic burden over time. Considering the high prevalence of undetected diabetes mellitus among patients seen by cardiologists and the widespread dysglycaemia in the general population, the issue raised by this study is indeed relevant for everyday practice.2,3

Relationship between higher than optimal glycaemia and cardiovascular diseases

The relationship between cardiovascular disease and glucose regulation abnormalities has been discussed since the first published report on glucosuria in patients with myocardial infarction in 1922.4 Thanks to individual and collaborative efforts of many research groups, the wealth of knowledge regarding association of . . . [Full Text of this Article]

Potential targets for risk reduction in patients with dysglycaemia

Recent evidence

Concluding remarks


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Related articles in EHJ:

Glycaemic control in newly diagnosed diabetes patients and mortality from ischaemic heart disease: 20-year follow-up of the HUNT Study in Norway
Ane Cecilie Dale, Kristian Midthjell, Tom Ivar Nilsen, Rune Wiseth, and Lars J. Vatten
EHJ 2009 30: 1372-1377. [Abstract] [Full Text]