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European Heart Journal Advance Access published online on July 18, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn338
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Good news on coronary computed tomographic angiography: answers that have questions!

Birgit Kantor1,*, Nandan S. Anavekar1 and Thomas C. Gerber2

1 Mayo Clinic, Rochester, MN 55905, USA
2 Mayo Clinic, Jacksonville, FL 32224, USA

* Corresponding author. Email: kantor.birgit@mayo.edu

This editorial refers to ‘Non-invasive diagnosis of ischaemic heart failure using 64-slice computed tomography,’ by S. Ghostine et al., doi:10.1093/eurheartj/ehn072

The first 10% of the full text of this article appears below.

An increasing number of studies have examined the role of coronary computed tomographic angiography (CCTA) in assessing patients with known or suspected coronary artery disease (CAD) relative to established evaluation approaches. The diagnostic and predictive value of stress electrocardiography, stress imaging, and invasive, selective coronary angiography (SCA) is documented by a large body of evidence, and their use to guide patient management is codified in clinical guidelines. To date, no convincing evidence suggests that the diagnostic or predictive value of CCTA is superior or even equivalent. Consequently, no first-line indications for CCTA exist.1,2 However, there may be niche applications where CCTA could be a potentially effective and cost-saving alternative to more established imaging techniques.

Studies comparing CCTA with SCA have universally shown a high negative predictive value (NPV).3 As a result, a ‘negative’ CCTA excludes CAD with very high certainty if image quality is . . . [Full Text of this Article]

CCTA for the assessment of unexplained cardiomyopathy

CCTA to ‘rule out’ disease


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Related articles in EHJ:

Non-invasive diagnosis of ischaemic heart failure using 64-slice computed tomography
Saïd Ghostine, Christophe Caussin, Michel Habis, Yacoub Habib, Chaoui Clément, Anne Sigal-Cinqualbre, Claude-Yves Angel, Bernard Lancelin, André Capderou, and Jean-François Paul
EHJ 2008 29: 2133-2140. [Abstract] [Full Text]