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European Heart Journal Advance Access originally published online on June 13, 2007
European Heart Journal 2007 28(16):2042-2043; doi:10.1093/eurheartj/ehm230
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

The consensus is clearly needed for the definition of stress hyperglycaemia in acute myocardial infarction: reply

Christophe Bauters on behalf of the REVE Investigators

Centre Hospitalier Régional et Universitaire de Lille
Faculté de Médecine de Lille
Hôpital Cardiologique
Boul. Prof. Leclercq
59037 Lille Cedex
France

Tel: +33 320445045 Fax: +33 320444881 E-mail address: cbauters{at}chru-lille.fr

We thank Dr Koracevic Goran for his comments on the definition of stress hyperglycaemia.1 We agree that different cut-off values have been used in the recent literature to define stress hyperglycaemia. As stated in our article, as there is no consensus, we used the median as the threshold value defining stress hyperglycaemia. However, we also performed statistical analyses using glycaemia on admission as a continuous variable. Using this approach, stress hyperglycaemia was associated with left ventricular remodelling in univariate as well as in multivariate analyses.2 Finally, although we agree that it would be interesting to determine the optimal cut-off value for risk prediction, an important cause of heterogeneity among studies is that some investigators restricted their analyses to non-diabetic patients, whereas others included all patients irrespective of diabetic status.

References

  1. Bauters C, Ennezat PV, Tricot O, Lauwerier B, Lallemant R, Saadouni H, Quandalle P, Jaboureck O, Lamblin N, Le Tourneau T. Stress hyperglycemia is an independent predictor of left ventricular remodeling after first anterior myocardial infarction in non-diabetic patients. Eur Heart J (2007) 28:546–552.[Abstract/Free Full Text]

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