Skip Navigation


European Heart Journal Advance Access originally published online on October 24, 2007
European Heart Journal 2007 28(22):2821-2822; doi:10.1093/eurheartj/ehm459
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
28/22/2821-a    most recent
ehm459v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bauters, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bauters, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Is stress hyperglycaemia a prognostic marker of left ventricular remodelling after first anterior myocardial infarction?: reply

Christophe Bauters on behalf of the REVE Investigators

Centre Hospitalier Régional et Universitaire de Lille Lille, France
Faculté de Médecine de Lille Lille, France
Hôpital Cardiologique CHRU de Lille Boul. Prof. Leclercq
59037 Lille Cedex
France

Tel: +33 320445045 Fax: +33 320444881 E-mail address: cbauters{at}chru-lille.fr

We thank Papadopoulos et al. for their interest in our manuscript. Their findings that stress hyperglycaemia was associated with left ventricular remodelling after anterior myocardial infarction (r = 0.471; P = 0.004) is indeed concordant with our results.1 The covariates that were available for inclusion into the multivariate models however differed and brain natriuretic peptide (BNP) levels were not routinely obtained in the REVE study.2 The demonstration that BNP plasma levels were significantly higher in patients with stress hyperglycaemia and that stress hyperglycaemia was not an independent predictor of left ventricular remodelling when BNP was included into the multivariable model is also interesting. BNP which has been previously associated with left ventricular remodelling3,4 could be the marker of choice in clinical practice. However, due to the limited number of patients in their data set (n = 40), we believe that the findings of Papadopoulos et al. are only hypothesis-generating and that further prospective studies are needed to determine the better biological marker(s) for risk prediction. Besides stress hyperglycaemia, markers of neurohormonal activation, inflammatory markers also would be interesting candidates for such a study.

References

  1. Bauters C, Ennezat PV, Tricot O, Lauwerier B, Lallemant R, Saadouni H, Quandalle P, Jaboureck O, Lamblin N, Le Tourneau T. Stress hyperglycaemia is an independent predictor of left ventricular remodelling after first anterior myocardial infarction in non-diabetic patients. Eur Heart J (2007) 28:546–552.[Abstract/Free Full Text]
  2. Savoye C, Equine O, Tricot O, Nugue O, Segrestin B, Sautiere K, Elkohen M, Pretorian EM, Taghipour K, Philias A, Aumegeat V, Decoulx E, Ennezat PV, Bauters C. Left ventricular remodeling after anterior wall acute myocardial infarction in modern clinical practice (from the REmodelage VEntriculaire [REVE] Study Group). Am J Cardiol (2006) 98:1144–1149.[CrossRef][Web of Science][Medline]
  3. Hole T, Hall C, Skaerpe T. N-terminal proatrial natriuretic peptide predicts two-year remodelling in patients with acute transmural myocardial infarction. Eur Heart J (2004) 25:416–423.[Abstract/Free Full Text]
  4. Hirayama A, Kusuoka H, Yamamoto H, Sakata Y, Asakura M, Higuchi Y, Mizuno H, Kashiwase K, Ueda Y, Okuyama Y, Hori M, Kodama K. Usefulness of plasma brain natriuretic peptide concentration for predicting subsequent left ventricular remodeling after coronary angioplasty in patients with acute myocardial infarction. Am J Cardiol (2006) 98:453–457.[CrossRef][Web of Science][Medline]

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?



This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
28/22/2821-a    most recent
ehm459v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bauters, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bauters, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?