European Heart Journal Advance Access originally published online on April 25, 2008
European Heart Journal 2008 29(12):1591; doi:10.1093/eurheartj/ehn179
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N-acetylcysteine for the prevention of postoperative atrial fibrillation: a prospective, randomized, placebo-controlled pilot study: reply
Departments of Cardiology
School of Medicine
Suleyman Demirel University
Kurtulus Mah, 122. cad. Hatice Halici apt. no: 126
32040 Isparta
Turkey
Tel: +90 532 413 9528
Fax: +90 246 232 6280
Email: mehmetozaydin{at}hotmail.com
Department of Cardiovascular Surgery
School of Medicine
Suleyman Demirel University
Isparta
Turkey
We would like to thank Dr Erdogan for his careful reading and his kind interest in our manuscript.1 As he stated in his letter, although an AF duration of >5 min was accepted as endpoint in the study, it seems that patients with AF episodes <5 min duration were also included in the control group according to Table 3.
We exluded the patients with an AF duration of <5 min, and none of the patients in either group had an AF episode of <5 min. We would like to thank Dr Erdogan for helping us to correct a mistake: although it seems that the range of duration in control group is 1–240 min (Table 3), however, it is actually 10–240 min. We realized that we made a typing error while prepairing the manuscript. We apologize for the mistake.
The rhythm was continuously recorded by telemetry during the first 2 postoperative days in the intensive care unit. It was continuously monitored and alarm-triggered abnormal rhythms were printed out by cardiac surgery team, which was not included in the study. The printouts of abnormal rhythms were consulted with blinded cardiologists. Rhythm strips were also retrospectively evaluated and reviewed on a daily basis by blinded cardiologists.
Reference
- Ozaydin M, Peker O, Erdogan D, Kapan S, Turker Y, Varol E, Ozguner F, Dogan A, Ibrisim E. N-acetylcysteine for the prevention of postoperative atrial fibrillation: a prospective, randomized, placebo-controlled pilot study. Eur Heart J (2008) 29:625–631.
[Abstract/Free Full Text]
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