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European Heart Journal 1999 20(6):406-420; doi:10.1053/euhj.1998.1308
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Review

Cell cycle regulatory molecules (cyclins, cyclin-dependent kinases and cyclin-dependent kinase inhibitors) and the cardiovascular system; potential targets for therapy?

J.-M. Lia,f1 and G. Brooksa,b,f2

a Cardiovascular Cellular and Molecular Biology, Cardiovascular Research, The Rayne Institute, St. Thomas’ Hospital, London
b Division of Cell and Molecular Biology, School of Animal and Microbial Sciences, University of Reading, WhiteknightsReading, Reading, U.K.

revised September 7, 1998; accepted September 9, 1998

Key Words: cardiac myocyte, cyclin, cyclin-dependent kinase, cyclin-dependent kinase inhibitor, hypertrophy, vascular smooth muscle cell

f1 Correspondence: Dr Gavin Brooks, Division of Cell and Molecular Biology, School of Animal and Microbial Sciences, University of Reading, P.O. Box 228, Reading, Berkshire RG6 6AJ, U.K.

f2 Present address: Cardiovascular Medicine, King’s College School of Medicine and Dentistry, Bessemer Road, London, U.K.

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Suppression of proliferation and cardiomyocyte hypertrophy by CHAMP, a cardiac-specific RNA helicase
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Gene therapy for coronary restenosis: is the enthusiasm justified?
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