Copyright © 1999 by the European Society of Cardiology.
Three-dimensional Doppler. Techniques and clinical applications
a Abteilung für Herzchirurgie, University of Heidelberg, Heidelberg, Germany
b Department of Medical and Biological Informatics, Deutsches Krebsforschungszentrum, Heidelberg, Germany
revised September 24, 1998; accepted September 30, 1998
Abstract
Aims
Colour Doppler is the most widely used technique for assessing valve disease, but eccentric regurgitant jets cannot be visualized and measured by conventional 2D techniques. We have developed a new procedure for three-dimensional (3D) reconstruction of colour Doppler signals.
Methods and Results
Fifty patients with mitral regurgitation underwent transoesophageal echocardiography and 3D acquisition. The severity of mitral regurgitation was assessed by angiography and the regurgitant volumes were measured by pulsed Doppler. The jet areas were calculated by planimetry from conventional colour Doppler; the jet volumes were obtained by 3D Doppler. A higher degree of mitral regurgitation was found in the patients with eccentric jets. While jet areas showed poor correlation with regurgitant volumes (r=0·61), jet volumes correlated significantly with regurgitant volumes (r=0·93;P<0·001). While jet areas failed to identify patients with different grades of regurgitation, jet volumes could so discriminate.
Conclusions
3D Doppler revealed new patterns of regurgitant flow and allowed a more accurate semiquantitative assessment of complex asymmetrical regurgitant jets. Three-dimensional colour Doppler has a great potential for becoming a reference method for the assessment of patients with heart valve disease.
Key Words: Three-dimensional echocardiography, colour Doppler, Heart valve disease, mitral regurgitation
f1 Correspondence:Raffaele De Simone, MD, University of Heidelberg, Abteilung für Herzchirurgie, Im Neuenheimer Feld, 120, D-69120 Heidelberg, Germany.
References
- Ghosh A, Nanda N, Maurer G. Three-dimensional reconstruction of echocardiographic images using the rotation method. Ultrasound Med Biol. 1982;6:655661
- Pandian NG, Nanda N, Schwartz S. Three-dimensional and four-dimensional transesophageal echocardiographic imaging of the heart and aorta in humans using a computed tomographic imaging probe. Echocardiography. 1992;9:677687[Web of Science][Medline]
- Levine RA, Weyman AE, Handschumacher MD. Three-dimensional echocardiography: techniques and applications. Am J Cardiol. 1992;69:121H130H[CrossRef][Medline]
- Vogel M, Ho SY, Anderson RH. Comparison of three dimensional echocardiographic findings with anatomical specimens of various congenitally malformed hearts. Br Heart J. 1995;73:566570
[Abstract/Free Full Text] - Schwartz SL, Cao QL, Azevedo J, Pandian NG. Simulation of intraoperative visualization of cardiac structures and study of dynamic surgical anatomy with real-time three-dimensional echocardiography. Am J Cardiol. 1994;73:501507[CrossRef][Web of Science][Medline]
- Gopal AS, Shen Z, Sapin PM. Assessment of cardiac function by three-dimensional echocardiography compared with conventional noninvasive methods. Circulation. 1995;92:842853
[Abstract/Free Full Text] - Jiang L, Siu SC, Handschumacher MD. Three-dimensional echocardiography. In vivo validation for right ventricular volume and function. Circulation. 1994;89:23422350
[Abstract/Free Full Text] - Siu SC, Rivera JM, Guerrero JL. Three-dimensional echocardiography. In vivo validation for left ventricular volume and function. Circulation. 1993;88:17151723
[Abstract/Free Full Text] - Nosir YF, Fioretti PM, Vletter WB. Accurate measurement of left ventricular ejection fraction by three-dimensional echocardiography. A comparison with radionuclide angiography. Circulation. 1996;94:460466
[Abstract/Free Full Text] - Buck T, Schon F, Baumgart D. Tomographic left ventricular volume determination in the presence of aneurysm by three-dimensional echocardiographic imaging. I: Asymmetric model hearts. J Am Soc Echocardiogr. 1996;9:488500[CrossRef][Medline]
- Sapin PM, Schroder KM, Gopal AS, Smith MD, DeMaria AN, King DL. Comparison of two- and three-dimensional echocardiography with cineventriculography for measurement of left ventricular volume in patients. J Am Coll Cardiol. 1994;24:10541063[Abstract]
- Delabays A, Sugeng L, Pandian NG. Dynamic three-dimensional echocardiographic assessment of intracardiac blood flow jets. Am J Cardiol. 1995;76:10531058[CrossRef][Web of Science][Medline]
- Sellers RD, Levy MJ, Amplatz L, Lillehei CW. Left retrograde cardioangiography in acquired cardiac disease. Am J Cardiol. 1964;14:432442
- Lewis JF, Kuo LC, Nelson JG, Limacher MC, Quinones MA. Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window. Circulation. 1984;70:425431
[Abstract/Free Full Text] - Ascah KJ, Stewart WJ, Jiang L. Doppler two-dimensional echocardiographic method for quantitation of mitral regurgitation. Circulation. 1985;72:377383
[Abstract/Free Full Text] - Chen C, Thomas JD, Anconina J. Impact of impinging wall jet on color Doppler quantification of mitral regurgitation. Circulation. 1991;84:712720
[Abstract/Free Full Text] - Pal NR, Pal SK. Entropic thresholding. Sig Proc. 1989;16:10531058
- Meinzer HP, Meetz K, Scheppelmann D, Engelmann U, Baur HJ. The Heidelberg Raytracing Model. IEEEComp Graph Appl. 1991;6:3443
- Vahl CF, Meinzer HP, Hagl S. Three-dimensional presen-tation of cardiac morphology. Thorac Cardiovasc Surg. 1991;39:198204
- Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307310[CrossRef][Web of Science][Medline]
- De Simone R, Glombitza G, Albers J. Three-dimensional reconstruction and quantitative analysis of color doppler jets in original color coding (Abstr). Echocardiography. 1997;14:S31
- Bolger AF, Eigler NL, Maurer G. Quantifying valvular regurgitation: limitations and inherent assumptions of Doppler techniques. Circulation. 1988;78:13161318
[Free Full Text] - Omoto R, Yokote Y, Takamoto S. The development of real-time two-dimensional Doppler echocardiography and its significance in acquired valvular diseases with specific reference to the evaluation of valvular regurgitation. Jpn Heart J. 1984;25:325340[Medline]
- Sahn DJ. Real-time two dimensional echocardiographic flow mapping. Circulation. 1985;71:849853
[Free Full Text] - Miyatake K, Izumi S, Okamoto M. Semiquantitative grading of severity of mitral regurgitation by real-time two-dimensional Doppler flow imaging technique. J Am Coll Cardiol. 1986;7:8288[Abstract]
- De Simone R, Lange R, Tanzeem A, Gams E, Saggau W, Hagl S. Intraoperative transesophageal echocardiography for the evaluation of mitral, aortic and tricuspid valve repair. A tool to optimize the surgical outcome. Eur J Cardiothorac Surg. 1992;6:665673[Abstract]
- De Simone R, Lange R, Tanzeem A, Gams E, Hagl S. Adjustable tricuspid valve annuloplasty assisted by intra-operative transesophageal color Doppler echocardiography. Am J Cardiol. 1993;71:926931[CrossRef][Web of Science][Medline]
- De Simone R. Atlas of transesophageal color Doppler echocardiography and intraoperative imaging. Berlin, Heidelberg, New York: Springer-Verlag; 1994.
- Croft CH, Lipscomb K, Mathis K. Limitations of qualitative angiographic grading in aortic or mitral regurgitation. Am J Cardiol. 1984;53:15931598[CrossRef][Web of Science][Medline]
- Belohlavek M, Foley D, Gerber T, Greenleaf J, Seward J. Three-dimensional reconstruction of color Doppler jets in the human heart. J Am Soc Echocardiogr. 1994;7:553560[Medline]
- Bohs LN, Friemel BH, Kisslo J, Harfe DT, Nightingale KR, Trahey GE. Three-dimensional flow images by reconstruction from two-dimensional vector velocity maps. J Am Soc Echocardiogr. 1995;8:915923[CrossRef][Medline]
- Legget ME, Martin RW, Sheehan FH. How positionally stable is a transesophageal echocardiographic probe? Implications for three-dimensional reconstruction. J Am Soc Echocardiogr. 1996;3:257265
This article has been cited by other articles:
![]() |
V. Gabriel, O. Kamp, and C. A. Visser Three-dimensional echocardiography in mitral valve disease Eur J Echocardiogr, December 1, 2005; 6(6): 443 - 454. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Mottl-Link, I. Wolf, M. Hastenteufel, S. Witte, H.-P. Meinzer, S. Hagl, and R. De Simone Non-invasive assessment of differences between bileaflet and tilting-disc aortic valve prostheses by 3D-Doppler profiles Interactive CardioVascular and Thoracic Surgery, October 1, 2005; 4(5): 383 - 387. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Hatle and G. R. Sutherland Regional myocardial function--a new approach. Eur. Heart J., August 1, 2000; 21(16): 1337 - 1357. [PDF] |
||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||


