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European Heart Journal 2000 21(1):14-16; doi:10.1053/euhj.1999.1835
Copyright © 2000 by the European Society of Cardiology.
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Editorial

Blockade of the renin angiotensin system in heart failure: the potential place of angiotensin II receptor blockers

D.J. van Veldhuisen and A.A. Voors

Department of Cardiology, Thoraxcentre, University Hospital Groningen, Utrecht, The Netherlands
Department of Cardiology, Thoraxcentre, University Hospital Diakonessehuis, Utrecht, The Netherlands

References

  1. Urata H, Healy B, Stewart RW, Bumpus FM, Husain A. Angiotensin II-forming pathways in normal and failing human hearts. Circ Res. 1990;66:883–890[Abstract/Free Full Text]
  2. Roig E, Perez-Villa F, Morales M. Clinical implications of increased plasma angiotensin II despite ACE inhibitors therapy in patients with congestive heart failure. Eur Heart J. 1999;20:53–57
  3. Swedberg L, Eneroth P, Kjekshus J, Wilhemsen L. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation. 1990;82:1730–1736[Abstract/Free Full Text]
  4. Gohlke P, Pees C, Unger T. AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension. 1998;31:349–355[Abstract/Free Full Text]
  5. Hamroff G, Katz SD, Mancini D. Addition of angiotesin II receptor blockade to maximal angiotensin-converting enzyme inhibition improves exercise capacity in patients with severe congestive heart failure. Circulation. 1999;99:990–992[Abstract/Free Full Text]
  6. Pitt B, Segal R, Martinez FA. Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). Lancet. 1997;349:747–752[CrossRef][Web of Science][Medline]

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This Article
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