European Heart Journal

European Heart Journal 2000 21(18):1502-1513; doi:10.1053/euhj.2000.2305
Copyright © 2000 by the European Society of Cardiology.

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Consensus Document

Myocardial infarction redefined—A consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction

Abstract

This document was developed by a consensus conference initiated by Kristian Thygesen, MD, and Joseph S. Alpert, MD, after formal approval by Lars Rydén, MD, President of the European Society of Cardiology (ESC), and Arthur Garson, MD, President of the American College of Cardiology (ACC). All of the participants were selected for their expertise in the field they represented, with approximately one-half of the participants selected from each organization. Participants were instructed to review the scientific evidence in their area of expertise and to attend the consensus conference with prepared remarks. The first draft of the document was prepared during the consensus conference itself. Sources of funding appear in Appendix A. The recommendations made in this document represent the attitudes and opinions of the participants at the time of the conference, and these recommendations were revised subsequently. The conclusions reached will undoubtedly need to be revised as new scientific evidence becomes available. This document has been reviewed by members of the ESC Committee for Scientific and Clinical Initiatives and by members of the Board of the ESC who approved the document on April 15, 2000.*

References

1. Bardales RH, Hailey LS, Xie SS, Schaefer RF, Hsu S-U. In situ apoptosis assay for the detection of early acute myocardial infarction. Am J Pathol. 1996;149:821–829[Abstract]
2. Buja LM. Modulation of the myocardial response to injury. Lab Invest. 1998;78:1345–1373[Web of Science][Medline]
3. Fishbein MC, Maclean D, Maroko PR. The histopathologic evolution of myocardial infarction. Chest. 1978;73:743–749
4. Jennings RB, Reimer KA. Factors involved in salvaging ischemic myocardium: effect of reperfusion of arterial blood. Circulation. 1983;68:I-25–36[Medline]
5. Jennings RB, Schaper J, Hill ML, Steenberger CJ, Reimer KA. Effect of reperfusion late in the phase of reversible ischemic injury: changes in cell volume, electrolytes, metabolites, and ultrastructure. Circ Res. 1985;56:262–278[Abstract/Free Full Text]
6. Kajstura J, Cheng W, Reiss K. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest. 1996;74:86–107[Web of Science][Medline]
7. Mallory GK, White PD, Salcedo-Salga J. The speed of healing of myocardial infarction: a study of the pathologic anatomy in 72 cases. Am Heart J. 1939;18:647–671[CrossRef][Web of Science]
8. Saraste A, Pulkki K, Kallajoki M, Hendriksen K, Parvinen M, Voipio-Pulkki L-M. Apoptosis in human acute myocardial infarction. Circulation. 1997;95:320–323[Abstract/Free Full Text]
1. Alexander JH, Sparapani RA, Mahaffey KW. Association between minor elevations of creatine-kinase-MB and mortality in patients with acute coronary syndromes without ST-segment elevation. JAMA. 2000;283:347–353[Abstract/Free Full Text]
2. Antman EM, Grudzien C, Mitchell RN, Sacks DB. Detection of unsuspected myocardial necrosis by rapid bedside assay for cardiac troponin T. Am Heart J. 1997;133:596–598[CrossRef][Web of Science][Medline]
3. Antman EM, Tanasijevic MJ, Thompson B. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med. 1996;335:1342–1349[Abstract/Free Full Text]
4. Apple FS, Falahati A, Paulson PR, Miller E, Sharkey SW. Improved detection of minor ischemic myocardial injury with measurement of serum cardiac troponin I. Clin Chem. 1997;43:2047–2051[Abstract/Free Full Text]
5. Apple FS. Clinical and analytical standardization issues confronting cardiac troponin I. Clin Chem. 1999;45:18–20[Free Full Text]
6. Apple FS. Tissue specificity of cardiac troponin I, cardiac troponin T, and creatine kinase MB. Clin Chim Acta. 1999;284:151–158[CrossRef][Web of Science][Medline]
7. Califf RM, Abdelmeguid AE, Kuntz RE. Myonecrosis after revascularization procedures. J Am Coll Cardiol. 1998;31:241–251[Abstract/Free Full Text]
8. Collinson PO. Troponin T or troponin I or CK-MB (or none?). Eur Heart J. 1998;19:N16–24[CrossRef][Web of Science][Medline]
9. Gerhardt W, Nordin G, Ljungdahl L. Can troponin T replace CK-MB mass as ‘gold standard’ for acute myocardial infarction (‘AMI’). Scand J Clin Lab Invest. 1999;59:83–89[CrossRef][Web of Science][Medline]
10. Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med. 1997;337:1648–1653[Abstract/Free Full Text]
11. Hamm CW, Heeschen C, Goldman B. Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. N Engl J Med. 1999;340:1623–1629[Abstract/Free Full Text]
12. Hamm CW, Ravkilde J, Gerhardt W. The prognostic value of serum troponin T in unstable angina. N Engl J Med. 1992;327:146–150[Abstract]
13. Harrington RA, Lincoff AM, Califf RM. Characteristics and consequences of myocardial infarction following percutaneous coronary intervention: insights from the Coronary Angioplasty Versus Excisional Atherectomomy Trial (CAVEAT). J Am Coll Cardiol. 1995;25:1693–1699[Abstract]
14. Ishikawa Y, Saffitz JE, Mealman TL, Grace AM, Roberts R. Reversible myocardial ischemic injury is not associated with increased creatine kinase activity in plasma. Clin Chem. 1997;43:467–475[Abstract/Free Full Text]
15. Lindahl B, Venge P, Wallentin L. Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. Circulation. 1996;93:1651–1657[Abstract/Free Full Text]
16. Ohman EM, Armstrong PW, Christenson RH. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med. 1996;335:1333–1341[Abstract/Free Full Text]
17. Ottani F, Galvani M, Ferrini D. Direct comparison of early elevations of cardiac troponin T and I in patients with clinical unstable angina. Am Heart J. 1999;137:284–291[CrossRef][Web of Science][Medline]
18. Ravkilde J, Horder M, Gerhardt W. Diagnostic performance and prognostic values of serum troponin T in suspected acute myocardial infarction. Scand J Clin Lab Invest. 1993;53:677–685[Web of Science][Medline]
19. Tardiff BE, Califf RM, Tcheng JE. Clinical outcomes after detection of elevated enzymes in patients undergoing percutaneous intervention: IMPACT-II trial (Integrilin [eptifibatide] to Minimize Platelet Aggregation and Coronary Thrombosis-II). J Am Coll Cardiol. 1999;33:88–96[Abstract/Free Full Text]
20. Wu AHB, Apple FS, Gibler WB, Jesse RL, Warshaw MM, Valdes R Jr. National Academy of Clinical Biochemistry Standards of Laboratory Practice: recommendations for use of cardiac markers in coronary artery disease. Clin Chem. 1999;45:1104–1121[Abstract/Free Full Text]
21. Zimmerman J, Fromm R, Meyer D. Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation. 1999;99:1671–1677[Abstract/Free Full Text]
1. Anderson WD, Wagner NB, Lee KL. Evaluation of a QRS scoring system for estimating myocardial infarct size. VI: Identification of screening criteria for non-acute myocardial infarcts. Am J Cardiol. 1988;61:729–733[CrossRef][Web of Science][Medline]
2. Chou T, Knilans T. Myocardial infarction: myocardial injury, and myocardial ischemia. Chou TC, Knilans TK. Electrocardiography in Clinical Practice: Adult and Pediatric. Philadelphia: W.B. Saunders; 1996. p. 121
3. Crow RS, Prineas RJ, Jacobs DR, Blackburn H. A new epidemiologic classification system for interim myocardial infarction from serial electrocardiographic changes. Am J Cardiol. 1989;64:454–461[CrossRef][Web of Science][Medline]
4. Menown IBA, MacKenzie G, Adgey AA. Optimizing the initial 12-lead electrocardiographic diagnosis of acute myocardial infarction. Eur Heart J. 2000;21:275–283[Abstract/Free Full Text]
5. Pahlm US, Chaitman BR, Rautaharju PM, Selvester RH, Wagner GS. Comparison of the various electrocardiographic scoring codes for estimating anatomically documented sizes of single and multiple infarcts of the left ventricle. Am J Cardiol. 1998;81:809–815[CrossRef][Web of Science][Medline]
6. Prineas RJ, Crow RJ, Blackburn H. Wright J. The Minnesota Code Manual of Electrocardiographic Findings: Standards and Procedures for Measurement and Classification. Boston: John Wright, PSG Inc; 1982. p. 1–229
7. Rautaharju PM, Park LP, Chaitman BR, Rautaharju F, Zhang ZM. The Novacode criteria for classification of ECG abnormalities and their clinically significant progression and regression. J Electrocardiol. 1998;31:157–187[Web of Science][Medline]
8. Selvester RH, Wagner GS, Hindman NB. The Selvester QRS scoring system for estimating myocardial infarct size: the development and application of the system. Arch Intern Med. 1985;145:1877–1881[Abstract/Free Full Text]
1. Beller GA. Assessment of myocardial viability. Curr Opin Cardiol. 1997;12:459–467[Web of Science][Medline]
2. Buda AJ. The role of echocardiography in the evaluation of mechanical complications of acute myocardial infarction. Circulation. 1991;84:I-109–121[Web of Science][Medline]
3. Duca MD, Giri S, Wu AHB. Comparison of acute rest myocardial perfusion imaging and serum markers of myocardial injury in patients with chest pain syndromes. J Nucl Cardiol. 1999;6:570–576[CrossRef][Web of Science][Medline]
4. Gibler WB, Runyon JP, Levy RC. A rapid diagnostic and treatment center for patients with chest pain in the emergency department. Ann Emerg Med. 1995;25:1–8[CrossRef][Web of Science][Medline]
5. Lieberman AN, Weiss JL, Jugdutt BI. Two-dimensional echocardiography and infarct size: relationship of regional wall motion and thickening to the extent of myocardial function in the dog. Circulation. 1981;63:739–746[Free Full Text]
6. Machecourt J, Longere P, Fagret D. Prognostic value of thallium-201 single-photon emission computed tomographic myocardial perfusion imaging according to extent of myocardial defect. J Am Coll Cardiol. 1994;23:1096–1106[Abstract]
7. Manoury C, Chen CC, Chua KB, Thompson CJ. Quantification of left ventricular function with thallium-201 and technetium-99m sestamibi myocardial gated SPECT. J Nucl Med. 1997;38:958–961[Abstract/Free Full Text]
8. Peels C, Visser CA, Funkekupper AJ, Visser FC, Roos JP. Usefulness of two-dimensional echocardiography for immediate detection of myocardial ischemia in the emergency room. Am J Cardiol. 1990;65:687–691[CrossRef][Web of Science][Medline]
9. Sabia P, Abbott RD, Afrookteh A, Keller MW, Touchtone DA, Kaul S. Importance to two-dimensional echocardiographic assessment of left ventricular systolic function in patients presenting to the emergency room with cardiac-related symptoms. Circulation. 1991;84:1615–1624[Abstract/Free Full Text]
10. Saeian K, Rhyne TL, Sagar KB. Ultrasonic tissue characterization for diagnosis of acute myocardial infarction in the coronary care unit. Am J Cardiol. 1994;74:1211–1215[CrossRef][Web of Science][Medline]
11. Tatum JL, Jesse RL, Kontos MC. Comprehensive strategy for the evaluation and triage of the chest pain patients. Ann Emerg Med. 1997;29:116–125[CrossRef][Web of Science][Medline]
1. Burke GL, Edlavitch SA, Crow RS. The effects of diagnostic criteria on trends in coronary heart disease morbidity: the Minnesota Heart Survey. J Clin Epidemiol. 1989;42:17–24[CrossRef][Web of Science][Medline]
2. Gillum RF, Fortmann SP, Prineas RJ, Kottke TE. International diagnostic criteria for acute myocardial infarction and acute stroke. Am Heart J. 1984;108:150–158[CrossRef][Web of Science][Medline]
3. McGovern PG, Pankow JS, Shaha E. Recent trends in acute coronary heart disease—mortality, morbidity, medical care and risk factors. N Engl J Med. 1966;334:884–890
4. Rose, GA, Blackburn, H, Cardiovascular survey methods, World Heart Organization, Geneva, Switzerland, 1968
5. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project: registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation. 1994;90:583–612[Abstract/Free Full Text]
6. Weinstein BJ, Epstein FH. Comparability of criteria and methods in the epidemiology of cardiovascular disease: report of a survey. Circulation. 1964;30:643[Free Full Text]
7. World Health Organization, Working Group on the Establishment of Ischemic Heart Disease Registers, 1971
8. Circulation. 1979;59:607–609[Free Full Text]
9. Porela P, Helenius H, Pulkki K, Voipio-Pulkki L-M. Epidemiological classification of acute myocardial infarction: time for a change? Eur Heart J. 1999;20:1459–1464[Abstract/Free Full Text]

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				N. Nesher, A. A. Alghamdi, S. K. Singh, J. Y. Sever, G. T. Christakis, B. S. Goldman, G. N. Cohen, F. Moussa, and S. E. Fremes Troponin after Cardiac Surgery: A Predictor or a Phenomenon? Ann. Thorac. Surg., April 1, 2008; 85(4): 1348 - 1354. [Abstract] [Full Text] [PDF]

				U. C. Rangasetty and C. Y. Lui Fractional flow reserve-guided intervention of angiographically nonsignificant coronary stenoses. J. Am. Coll. Cardiol., March 18, 2008; 51(11): 1123 - 1123. [Full Text] [PDF]

				P. O Collinson, G. H Gaynor, and D. C Gaze Cardiac troponin I measurement using the ACS:180 to predict four-year cardiac event rate Ann Clin Biochem, March 1, 2008; 45(2): 184 - 188. [Abstract] [Full Text] [PDF]

				L. G. Mellbin, K. Malmberg, A. Norhammar, H. Wedel, L. Ryden, and for the DIGAMI 2 Investigators The impact of glucose lowering treatment on long-term prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial Eur. Heart J., January 2, 2008; 29(2): 166 - 176. [Abstract] [Full Text] [PDF]

				M. Wallander, K. Malmberg, A. Norhammar, L. Ryden, and A. Tenerz Oral Glucose Tolerance Test: A Reliable Tool for Early Detection of Glucose Abnormalities in Patients With Acute Myocardial Infarction in Clinical Practice: A report on repeated oral glucose tolerance tests from the GAMI Study Diabetes Care, January 1, 2008; 31(1): 36 - 38. [Abstract] [Full Text] [PDF]

				V Novack, A B Jotkowitz, D Cutlip, G Amit, N Liebermann, and A Porath Transition from CK-MB to troponin did not improve the 1 year mortality of non-ST elevation acute coronary syndromes Postgrad. Med. J., January 1, 2008; 84(987): 50 - 55. [Abstract] [Full Text] [PDF]

				M. Grau, M. Guxens, I. Subirana, M. Fito, M.-I. Covas, B. Jacquemin, J. Sunyer, T. Lanki, S. Picciotto, T. Bellander, et al. South-to-North gradient in lipid peroxidation in men with stable coronary artery disease in Europe Eur. Heart J., December 1, 2007; 28(23): 2841 - 2849. [Abstract] [Full Text] [PDF]

				M. C. Tjandrawidjaja, Y. Fu, H. Al-Khalidi, T. G. Todaro, P. Adams, F. Van de Werf, C. B. Granger, P. W. Armstrong, and on behalf of the APEX-AMI Investigators Failure of investigator adherence to electrocardiographic entry criteria is frequent and influences clinical outcomes: lessons from APEX-AMI Eur. Heart J., December 1, 2007; 28(23): 2850 - 2857. [Abstract] [Full Text] [PDF]

				G. Ferrari, F. Olliveri, G. De Filippi, A. Milan, F. Apra, A. Boccuzzi, M. Converso, and P. Navalesi Noninvasive Positive Airway Pressure and Risk of Myocardial Infarction in Acute Cardiogenic Pulmonary Edema: Continuous Positive Airway Pressure vs Noninvasive Positive Pressure Ventilation Chest, December 1, 2007; 132(6): 1804 - 1809. [Abstract] [Full Text] [PDF]

				A. Norhammar, J. Lindback, L. Ryden, L. Wallentin, U. Stenestrand, and on behalf of the Register of Information and Knowl Improved but still high short- and long-term mortality rates after myocardial infarction in patients with diabetes mellitus: a time-trend report from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admission Heart, December 1, 2007; 93(12): 1577 - 1583. [Abstract] [Full Text] [PDF]

				J. J. Brugts, E. Boersma, M. Chonchol, J. W. Deckers, M. Bertrand, W. J. Remme, R. Ferrari, K. Fox, M. L. Simoons, and on behalf of the EUROPA Investigators The Cardioprotective Effects of the Angiotensin-Converting Enzyme Inhibitor Perindopril in Patients With Stable Coronary Artery Disease Are Not Modified by Mild to Moderate Renal Insufficiency: Insights From the EUROPA Trial J. Am. Coll. Cardiol., November 27, 2007; 50(22): 2148 - 2155. [Abstract] [Full Text] [PDF]

				N. Kilcullen, K. Viswanathan, R. Das, C. Morrell, A. Farrin, J. H. Barth, A. S. Hall, and for the EMMACE-2 Investigators Heart-Type Fatty Acid-Binding Protein Predicts Long-Term Mortality After Acute Coronary Syndrome and Identifies High-Risk Patients Across the Range of Troponin Values J. Am. Coll. Cardiol., November 20, 2007; 50(21): 2061 - 2067. [Abstract] [Full Text] [PDF]

				J. Alfredsson, U. Stenestrand, L. Wallentin, and E. Swahn Gender differences in management and outcome in non-ST-elevation acute coronary syndrome Heart, November 1, 2007; 93(11): 1357 - 1362. [Abstract] [Full Text] [PDF]

				C. Aboa-Eboule, C. Brisson, E. Maunsell, B. Masse, R. Bourbonnais, M. Vezina, A. Milot, P. Theroux, and G. R. Dagenais Job Strain and Risk of Acute Recurrent Coronary Heart Disease Events JAMA, October 10, 2007; 298(14): 1652 - 1660. [Abstract] [Full Text] [PDF]

				Task Force Members, K. Thygesen, J. S. Alpert, H. D. White, Biomarker Group, A. S. Jaffe, F. S. Apple, M. Galvani, H. A. Katus, L. K. Newby, et al. Universal definition of myocardial infarction: Kristian Thygesen, Joseph S. Alpert and Harvey D. White on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction Eur. Heart J., October 2, 2007; 28(20): 2525 - 2538. [Full Text] [PDF]

				A. Sestili, C. Coletta, V. Manno, S. Perna, M. Renzi, P. Romano, R. Ricci, and V. Ceci Restrictive mitral inflow pattern is a strong independent predictor of lack of viable myocardium after a first acute myocardial infarction Eur J Echocardiogr, October 1, 2007; 8(5): 332 - 440. [Abstract] [Full Text] [PDF]

				T. N. Martin, B. A. Groenning, H. M. Murray, T. Steedman, J. E. Foster, A. T. Elliot, H. J. Dargie, R. H. Selvester, O. Pahlm, and G. S. Wagner ST-Segment Deviation Analysis of the Admission 12-Lead Electrocardiogram as an Aid to Early Diagnosis of Acute Myocardial Infarction With a Cardiac Magnetic Resonance Imaging Gold Standard J. Am. Coll. Cardiol., September 11, 2007; 50(11): 1021 - 1028. [Abstract] [Full Text] [PDF]

				S. Arora Autonomic imbalance in patients with takotsubo cardiomyopathy: cause or association? QJM, September 1, 2007; 100(9): 593 - 594. [Full Text] [PDF]

				P. Erne, A. W. Schoenenberger, M. Zuber, D. Burckhardt, W. Kiowski, P. Dubach, T. Resink, and M. Pfisterer Effects of anti-ischaemic drug therapy in silent myocardial ischaemia type I: the Swiss Interventional Study on Silent Ischaemia type I (SWISSI I): a randomized, controlled pilot study Eur. Heart J., September 1, 2007; 28(17): 2110 - 2117. [Abstract] [Full Text] [PDF]

				C. Prontera, A. Fortunato, S. Storti, A. Mercuri, G. Longombardo, G. C. Zucchelli, M. Emdin, and A. Clerico Evaluation of Analytical Performance of the Siemens ADVIA TnI Ultra Immunoassay Clin. Chem., September 1, 2007; 53(9): 1722 - 1723. [Full Text] [PDF]

				F. Airoldi, A. Colombo, N. Morici, A. Latib, J. Cosgrave, L. Buellesfeld, E. Bonizzoni, M. Carlino, U. Gerckens, C. Godino, et al. Incidence and Predictors of Drug-Eluting Stent Thrombosis During and After Discontinuation of Thienopyridine Treatment Circulation, August 14, 2007; 116(7): 745 - 754. [Abstract] [Full Text] [PDF]

				R. Shah, J. Selter, Y. Wang, M. Greenspan, and J. M. Foody Association of Troponin Status With Guideline-Based Management of Acute Myocardial Infarction in Older Persons Arch Intern Med, August 13, 2007; 167(15): 1621 - 1628. [Abstract] [Full Text] [PDF]

				Authors/Task Force Members, J.-P. Bassand, C. W. Hamm, D. Ardissino, E. Boersma, A. Budaj, F. Fernandez-Aviles, K. A.A. Fox, D. Hasdai, E. M. Ohman, et al. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: The Task Force for the Diagnosis and Treatment of Non-ST-Segment Elevation Acute Coronary Syndromes of the European Society of Cardiology Eur. Heart J., July 1, 2007; 28(13): 1598 - 1660. [Full Text] [PDF]

				P. Schiano and P. Gabriel Steg Measurement and prevention of myocardial injury during percutaneous coronary intervention Heart, June 1, 2007; 93(6): 656 - 657. [Abstract] [Full Text] [PDF]

				D. N. Tziakas, J. C. Kaski, G. K. Chalikias, C. Romero, S. Fredericks, I. K. Tentes, A. X. Kortsaris, D. I. Hatseras, and D. W. Holt Total Cholesterol Content of Erythrocyte Membranes Is Increased in Patients With Acute Coronary Syndrome: A New Marker of Clinical Instability? J. Am. Coll. Cardiol., May 29, 2007; 49(21): 2081 - 2089. [Abstract] [Full Text] [PDF]

				P. Erne, A. W. Schoenenberger, D. Burckhardt, M. Zuber, W. Kiowski, P. T. Buser, P. Dubach, T. J. Resink, and M. Pfisterer Effects of Percutaneous Coronary Interventions in Silent Ischemia After Myocardial Infarction: The SWISSI II Randomized Controlled Trial JAMA, May 9, 2007; 297(18): 1985 - 1991. [Abstract] [Full Text] [PDF]

				A. E. Arai False positive or true positive troponin in patients presenting with chest pain but 'normal' coronary arteries: lessons from cardiac MRI Eur. Heart J., May 2, 2007; 28(10): 1175 - 1177. [Full Text] [PDF]

				C. D. Miller, A. Banerjee, K. W. Mahaffey, M. C. Kontos, G. Fermann, C. V. Pollack Jr., E. Antman, P. Aylward, S. G. Goodman, R. Santos, et al. Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial Eur. Heart J., May 1, 2007; 28(9): 1079 - 1084. [Abstract] [Full Text] [PDF]

				W S A Smellie, J Forth, S R S Smart, M J Galloway, W Irving, D Bareford, P O Collinson, K G Kerr, G Summerfield, P J Carey, et al. Best practice in primary care pathology: review 7 J. Clin. Pathol., May 1, 2007; 60(5): 458 - 465. [Abstract] [Full Text] [PDF]

				D. E. Cutlip, S. Windecker, R. Mehran, A. Boam, D. J. Cohen, G.-A. van Es, P. Gabriel Steg, M.-a. Morel, L. Mauri, P. Vranckx, et al. Clinical End Points in Coronary Stent Trials: A Case for Standardized Definitions Circulation, May 1, 2007; 115(17): 2344 - 2351. [Abstract] [Full Text] [PDF]

				N Sekhri, G S Feder, C Junghans, H Hemingway, and A D Timmis How effective are rapid access chest pain clinics? Prognosis of incident angina and non-cardiac chest pain in 8762 consecutive patients Heart, April 1, 2007; 93(4): 458 - 463. [Abstract] [Full Text] [PDF]

				A. Rocco, M. Pasquini, E. Cecconi, G. Sirimarco, M. C. Ricciardi, E. Vicenzini, M. Altieri, V. Di Piero, and G. L. Lenzi Monitoring After the Acute Stage of Stroke: A Prospective Study Stroke, April 1, 2007; 38(4): 1225 - 1228. [Abstract] [Full Text] [PDF]

				S C Griffin, J A Barber, A Manca, M J Sculpher, S G Thompson, M J Buxton, and H Hemingway Cost effectiveness of clinically appropriate decisions on alternative treatments for angina pectoris: prospective observational study BMJ, March 24, 2007; 334(7594): 624 - 624. [Abstract] [Full Text] [PDF]

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