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European Heart Journal 2000 21(23):1902-1903; doi:10.1053/euhj.2000.2436
Copyright © 2000 by the European Society of Cardiology.
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Editorial

Is more better? About dose levels of ACE inhibitors in chronic heart failure

K. Swedberg

Department of Medicine, Sahlgrenska University Hospital/Östra, Göteborg, Sweden

References

  1. Flather M, Yusuf S, Kober L. Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group. Lancet. 2000;355:1575–1581[CrossRef][ISI][Medline]
  2. Lancet. 1999;353:9–13[CrossRef][ISI][Medline]
  3. Lancet. 1999;353:2001–2007[CrossRef][ISI][Medline]
  4. Packer M. Pathophysiology of chronic heart failure. Division of Circulatory Physiology, Columbia University, College of Physicians and Surgeons, New York, NY 10032. Lancet. 1992;340:88–92[CrossRef][ISI][Medline]
  5. Pitt B, Zannad F, Remme WJ. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999;341:709–717[Abstract/Free Full Text]
  6. Garg R, Yusuf S. Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor. JAMA. 1995;273:1450–1456[Abstract/Free Full Text]
  7. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:145–153[Abstract/Free Full Text]
  8. Pacher R, Globits S, Bergler Klein J. Clinical and neurohumoral response of patients with severe congestive heart failure treated with two different captopril dosages. Eur Heart J. 1993;14:273–278[Abstract/Free Full Text]
  9. MacFayden RJ, Lee AF, Morton JJ, Pringle SD, Struthers AD. How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure? Heart. 1999;82:57–61[Abstract/Free Full Text]
  10. Packer M, Poole-Wilson PA, Armstrong PW. Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. Circulation. 1999;100:2312–2318[Abstract/Free Full Text]
  11. Rydén L, Armstrong PW, Cleland JG. Efficacy and safety of high-dose lisinopril in chronic heart failure patients at high cardiovascular risk, including those with diabetes mellitus. Results from the ATLAS trial. Eur Heart J. 2000;21:1967–1978[Abstract/Free Full Text]

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This Article
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Right arrow Email this article to a friend
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Right arrow Articles by Swedberg, K.
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PubMed
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Right arrow Articles by Swedberg, K.
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