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European Heart Journal 2000 21(8):654-661; doi:10.1053/euhj.1999.1853
Copyright © 2000 by the European Society of Cardiology.
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Videodensitometric quantitative angiography after coronary balloon angioplasty, compared to edge-detection quantitative angiography and intracoronary ultrasound imaging

R.J.G Petersa,f1, W.E.M Koka, G Pasterkampb, C Von Birgelenc, M Prinsd and P.W Serruysc

a Academic Medical Center, Department of Cardiology
b InterUniversity Cardiology Institute of the Netherlands, Utrecht
c Thoraxcenter, Division of Cardiology, Erasmus University, Rotterdam, The Netherlands
d Department of Clinical Epidemiology, University of Amsterdam, Amsterdam

revised August 3, 1999; accepted August 4, 1999

Abstract

Aims To assess the value of videodensitometric quantification of the coronary lumen after angioplasty by comparison to two other techniques of coronary artery lumen quantification.

Methods and Results Videodensitometric quantitative angiography, edge detection quantitative angiography and 30MHz intracoronary ultrasound imaging were performed after successful balloon angioplasty in 161 patients. Lumen cross-sectional areas were mean (SD) 2·82 (1·15)mm2for edge detection quantitative angiography, 3·67 (1·5)mm2for videodensitometric quantitative angiography and 5·32 (1·75)mm2for intracoronary ultrasound imaging (P<0·001). The correlation between intracoronary ultrasound imaging and videodensitometric quantitative angiography (r=0·44) was almost similar to that of intracoronary ultrasound imaging and edge detection quantitative angiography (r=0·47). The correlation between the three techniques was not significantly influenced by the presence of ruptures and dissections on intracoronary ultrasound imaging. The absence of calcifications improved the correlation between videodensitometry and intracoronary ultrasound imaging.

Conclusions The luminal dimensions as measured by videodensitometric quantitative angiography matched intracoronary ultrasound imaging derived dimensions more closely than edge detection quantitative angiography. Videodensitometric quantitative angiography represents an on-line alternative to intracoronary ultrasound imaging for quantitative analysis regardless of the degree of vessel damage.

Key Words: Videodensitometry, quantitative coronary angiography, intravascular ultrasound imaging, balloon angioplasty

f1 Correspondence: Ron J. G. Peters, MD, Department of Cardiology, Room F3-236, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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