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European Heart Journal 2001 22(11):977-978; doi:10.1053/euhj.2000.2527
Copyright © 2001 by the European Society of Cardiology.
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Letter to the Editors

Trimetazidine in AMI

G.D. Lopaschuk

Cardiovascular Research Group, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada

References

  1. Eur Heart J. 2000;18:1537–1546
  2. Tognoni G. Editorial. Eur Heart J. 2000;18:1498–1499
  3. McLellan KJ, Plsoker GL. Trimetazidine: A review of its use in stable angina pectoris and other coronary conditions. Drugs. 1999;58:143–157[CrossRef][Web of Science][Medline]
  4. Maridonneau-Parini I, Harpey C. Effect of trimetazidine on membrane damage induced by oxygen radicals in human red cells. Br J Clin Pharmacol. 1985;20:148–151[Web of Science][Medline]
  5. Kantor P, Lucien A, Kozak R, Lopaschuk GD. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res. 2000;86:580–588[Abstract/Free Full Text]
  6. El Banani H, Bernard M, Baetz D. Changes in intracellular sodium and pH during ischaemia-reperfusion are attenuated by trimetazidine. Comparison between low- and zero-flow ischaemia. Cardiovasc Res. 2000;47:688–696[Abstract/Free Full Text]
  7. Stanley W, Lopaschuk GD, Hall JL, McCormack JG. Regulation of myocardial carbohydrate metabolism under normal and ischemic conditions: Potential for pharmacological interventions. Cardiovasc Res. 1997;33:243–257[Free Full Text]
  8. Fath-ordoubadi F, Beatt KJ. Glucose-insulin-potassium therapy for treatment of acute myocardial infarction. An overview of randomized placebo-controlled trials. Circulation. 1997;96:1152–1156[Abstract/Free Full Text]
  9. Diaz R, Paolasso ED, Piegas LS. Metabolic modulation of acute myocardial infarction. The ECLA Glucose-Insulin-Potassium Pilot Trial. Circulation. 1998;98:2227–2234[Abstract/Free Full Text]

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This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
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ISI Web of Science (1)
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Right arrow Articles by Lopaschuk, G.D.
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PubMed
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Right arrow Articles by Lopaschuk, G.D.
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