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European Heart Journal 2001 22(14):1151-1153; doi:10.1053/euhj.2001.2598
Copyright © 2001 by the European Society of Cardiology.
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Editorials

Coronary angiogenesis: dipyridamole is back on the stage?

F. Lombardi and R. Rambaldi

Osp. S. Paolo, University of Milan, Milan, Italy

References

  1. Bombardini T, Picano E. The coronary angiogenetic effect of heparin: experimental basis and clinical evidence. Angiology. 1997;48:969–976[ISI][Medline]
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  3. Symons JD, Firoozmand E, Longhurst JC. Repeated dipyridamole administration enhances collateral-dependent flow and regional function during exercise. A role for adenosine. Cir Res. 1993;73:503–513[Abstract/Free Full Text]
  4. Picano E, Michelassi C. Chronic oral dipyridamole as a ‘novel’ antianginal drug: the collateral hypothesis. Cardiovasc Res. 1997;33:666–670[Abstract/Free Full Text]
  5. Sacks HS, Ancona-Berk VA, Berrier J, Nagalingam R, Chalmers TC. Dipyridamole in the treatment of angina pectoris: a meta-analysis. Clin Pharmacol Ther. 1988;43:610–615[ISI][Medline]
  6. Tornling G, Unge G, Skoog L, Ljungqvist A, Carlsson S, Adolfsson J. Proliferative activity of myocardial capillary wall cells in dipyridamole-treated rats. Cardiovasc Res. 1978;12:692–695[ISI][Medline]
  7. Tornling G, Unge G, Adolfsson J, Ljungqvist A, Carlsson S. Proliferative activity of capillary wall cells in skeletal muscles of rats during long-term treatment with dipyridmole. Arzneimittelforschung. 1980;30:622–623[Medline]
  8. Torry RJ, O'Brien DM, Connel PM, Tomanek RJ. Dipyridamole-induced capillary growth in normal and hypertrophic hearts. Am J Physiol. 1992;262:H980–H986
  9. Belardinelli R, Belardinelli L, Shryock JC. Effects of dypiridamole on coronary collateralization and myocardial perfusion in patients with ischaemic cardiomyopathy. Eur Heart J. 2001;22:1205–1213[Abstract/Free Full Text]
  10. Khouri EM, Gregg DE, McGranahan GM. Regression and reappearance of coronary collaterals. Am J Physiol. 1971;220:655–661[Free Full Text]

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Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. H. Adair
Growth regulation of the vascular system: an emerging role for adenosine
Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2005; 289(2): R283 - R296.
[Abstract] [Full Text] [PDF]


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