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European Heart Journal 2001 22(16):1514-1515; doi:10.1053/euhj.2000.2524
Copyright © 2001 by the European Society of Cardiology.
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Letters to the Editor

Cholesterol reduction, statins and the cytochrome P-450 system. No more recipes please

M. Bortolini

Basel, Switzerland

References

  1. Cockcroft JR, Wilkinson IB. Cholesterol reduction, statins and the cytochrome P-450 system (letter). Eur Heart J. 2000;21:1555–1556[Free Full Text]
  2. Horsmans Y. Differential metabolism of statins: importance in drug–drug interactions. Eur Heart J Supplements. 1999;1:T7–T12
  3. Yeo KR, Yeo WW, Wallis EJ, Ramsay LE. Enhanced cholesterol reduction by simvastatin in diltiazem-treated patients. Br J Clin Pharm. 1999;48:610–615[CrossRef][Web of Science][Medline]
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  5. Flint OP, Masters BA, Gregg RE, Durham SK. HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgerantylation of low-molecular-weight proteins in neonatal rat muscle cell culture. Toxicol Appl Pharmacol. 1997;145:99–100[CrossRef][Web of Science][Medline]
  6. Pierno S, De Luca A, Liantonio A, Camerino C, Conte Camerino D. Effects of HMG-CoA reductive inhibitors on excitation-contraction coupling of rat skeletal muscle. Eur J Pharmacol. 1999;364:43–48[CrossRef][Web of Science][Medline]
  7. Simatupang A, Lindenthal B, von Bergmann J, von Bergmann K. Differences in the effect of simvastatin and pravastatin on cholesterol metabolism in patient with hypecholesterolemia (Abstr). Atherosclerosis. 1997;134:220
  8. Davidson MH, Stein EA, Dujovne CA. The efficacy and six week tolerability of simvastatin 80- and 160mg/day. Am J Cardiol. 1997;79:38–42[Web of Science][Medline]
  9. The Pink Sheet. 1997;:
  10. Bottorff M, Hansten P. Long-term safety of hepatic hydroxymethyl glutaryl coenzyme A reductase inhibitors. The role of metabolism—monograph for physicians. Arch Intern Med. 2000;160:2273–2280[Free Full Text]
  11. Dressrer GK, Spence JD, Bailey DG. Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition. Clin Pharmacokinet. 2000;38:41–57[CrossRef][Web of Science][Medline]

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This Article
Right arrow FREE Full Text (PDF) Freely available
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Right arrow Alert me when E-letters are posted
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Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
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Google Scholar
Right arrow Articles by Bortolini, M.
Right arrow Search for Related Content
PubMed
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Right arrow Articles by Bortolini, M.
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What's this?