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European Heart Journal 2001 22(17):1517-1518; doi:10.1053/euhj.2001.2659
Copyright © 2001 by the European Society of Cardiology.
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Editorials

Antibodies against oxidized LDL for non-invasive diagnosis of atherosclerotic vascular disease

B. de Geest and D. Collen

Center for Molecular and Vascular Disease, University of Leuven, Belgium

References

  1. Holvoet P, Vanhaecke J, Janssens S, Van de Werf F, Collen D. Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation. 1998;98:1487–1494[Abstract/Free Full Text]
  2. Holvoet P, Collen D, Van de Werf F. Malondialdehyde-modified LDL as a marker of acute coronary syndromes. JAMA. 1999;281:1718–1721[Abstract/Free Full Text]
  3. Salonen JT, Yla-Herttuala S, Yamamoto R. Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet. 1992;339:883–887[CrossRef][ISI][Medline]
  4. Puurunen M, Manttari M, Manninen V. Antibody against oxidized low-density lipoprotein predicting myocardial infarction. Arch Intern Med. 1994;154:2605–2609[Abstract]
  5. Bergmark C, Wu R, de Faire U, Lefvert AK, Swedenborg J. Patients with early-onset peripheral vascular disease have increased levels of autoantibodies against oxidized LDL. Arterioscler Thromb Vasc Biol. 1995;15:441–445[Abstract/Free Full Text]
  6. Maggi E, Finardi G, Poli M. Specificity of autoantibodies against oxidized LDL as an additional marker for atherosclerotic risk. Coronary Art Dis. 1993;4:1119–1122[ISI][Medline]
  7. Virella G, Virella I, Leman RB, Pryor MB, Lopes-Virella MF. Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers. Int J Clin Lab Res. 1993;23:95–101[ISI][Medline]
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  9. Orchard TJ, Virella G, Forrest KY, Evans RW, Becker DJ, Lopes-Virella MF. Antibodies to oxidized LDL predict coronary artery disease in type 1 diabetes: a nested case-control study from the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes. 1999;48:1454–1458[Abstract]
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  11. Lopes-Virella MF, Koskinen S, Mironova M. The preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA. Atherosclerosis. 2000;152:107–115[CrossRef][ISI][Medline]
  12. Seccia M, Albano E, Maggi E, Bellomo G. Circulating autoantibodies recognizing peroxidase-oxidized low density lipoprotein. Evidence for new antigenic epitopes formed in vivo independently from lipid peroxidation. Arterioscler Thromb Vasc Biol. 1997;17:134–140[Abstract/Free Full Text]
  13. Virella G, Koskinen S, Krings G, Onorato JM, Thorpe SR, Lopes-Virella M. Immunochemical characterization of purified human oxidized low-density lipoprotein antibodies. Clin Immunol. 2000;95:135–144[CrossRef][ISI][Medline]
  14. Chang MK, Bergmark C, Laurila A. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Proc Natl Acad Sci USA. 1999;96:6353–6358[Abstract/Free Full Text]
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  16. Shaw PX, Horkko S, Chang MK. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J Clin Invest. 2000;105:1731–1740[ISI][Medline]
  17. George J, Ahmed A, Patnaik M. The prediction of coronary atherosclerosis employing artificial neural networks. Clin Cardiol. 2000;23:453–456[ISI][Medline]

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This Article
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Right arrow Articles by de Geest, B.
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