Copyright © 2001 by the European Society of Cardiology.
Transcatheter coil occlusion of the arterial duct. Results of the European Registry
a Department of Paediatric Cardiology, Guy's Hospital, London, U.K
b Department of Public Health Medicine, Guy's Hospital, London, U.K
revised January 12, 2001; accepted January 17, 2001
Abstract
Aims To report on the data, collected by the Association for European Paediatric Cardiology (AEPC) Registry, on transcatheter coil occlusion of the arterial duct.
Methods and Results A retrospective study was conducted of intention-to-treat data from 30 European and Middle Eastern tertiary referral centres which included an analysis of causes of suboptimal outcome. Since 1994, reports have been made on 1291 attempted coil occlusions of the arterial duct in 1258 patients. Median age at procedure was 4 years (range 0·1–52) and median weight was 29kg (range 1·8–100). Following coil implantation, the immediate occlusion rate was 59%, which rose to 95% at 1 year. A suboptimal outcome occurred on 129 occasions (10% of procedures) and was defined as coil embolization, an abandoned procedure, persistent haemolysis, residual leak requiring a further procedure, flow impairment in adjacent structures and duct re-canalization. A number of clinical factors were chosen but only increasing duct size [odds ratio of 2·6:1 (CI 2–3·2)] and the presence of a tubular shaped duct [odds ratio 2·4:1 (CI 1·4–4)] were positively associated with an unfavourable outcome.
Conclusion The results of the European Registry support the view that transcatheter coil occlusion of the persistent arterial duct is a safe and effective procedure. Unfavourable outcomes are more likely when closing larger and/or tubular shaped ducts.
Key Words: Persistent arterial duct, transcatheter coil occlusion
f1 Correspondence: Dr A. G. Magee, Department of Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, U.K.
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