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European Heart Journal 2001 22(5):353-354; doi:10.1053/euhj.2000.2447
Copyright © 2001 by the European Society of Cardiology.
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Editorial

Ionic or non-ionic contrast during coronary intervention: does it make a difference?

V. Legrand

CHU, Liege, Belgium

References

  1. Robertson JF. Blood clot formation and angiographic syringes containing non-ionic contrast media. Radiology. 1987;163:621–622
  2. Gabriel DA, Jones MR, Reece NS, Boothroyd E, Bashore T. Platelet and fibrin modification by radiographic contrast media. Circ Res. 1991;68:881–887[Abstract/Free Full Text]
  3. Chronos NA, Goodall AH, Wilson DJ, Sigwart U, Buller NP. Profound platelet degranulation is an important side effect of some types of contrast media used in interventional cardiology. Circulation. 1993;88:2035–2044[Abstract/Free Full Text]
  4. Stormorken H, Sakariassen KS. In vitro platelet degranulation by contrast media: clinical relevance? Circulation. 1994;90:1580–1581[Medline]
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  8. Melton LG, Dehmer GJ, Gabriel DA. Alterations in fibrin detected in coronary sinus blood after heparin and coronary angiography with a non ionic contrast agent (iohexol). Am J Cardiol. 1998;82:295–298[CrossRef][ISI][Medline]
  9. Pureshi NR, Den Heijer P, Crijns HJGM. Percutaneous coronary angioscopy comparison of thrombus formation during percutaneous coronary angioplasty with ionic and non ionic low osmolality contrast media in unstable angina. Am J Cardiol. 1997;90:700–704
  10. Piessens JH, Stranmmen F, Vrolix MC, Glazier JJ, Benit C, De Geest H, Willems JL. Effects of an ionic versus a non ionic low osmolar contrast agent on the thrombotic complications of coronary angioplasty. Cathet Cardiovasc Diagn. 1993;28:99–105[ISI][Medline]
  11. Grines CL, Schreiber TL, Savas V. A randomized trial of low osmolar ionic versus non ionic contrast media in patients with myocardial infarction or unstable angina undergoing percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1996;27:1381–1386[Abstract]
  12. Esplugas E, Cequier A, Jara F, Mauri J, Soler T, Sala J, Sabate X. Risk of thrombosis during coronary angioplasty with low osmolality contrast media. Am J Cardiol. 1991;68:1020–1024[CrossRef][ISI][Medline]
  13. Schräder R, Esch I, Ensolen R, Fach WA, Merle H, Scherer D, Sievert H, Spies HF, Zeplin HE. A randomized trial comparing the impact of a nonionic (iomeprol) versus an ionic (ioxaglate) low osmolar contrast medium on abrupt vessel closure and ischemic complications after coronary angioplasty. J Am Coll Cardiol. 1999;33:395–402[Abstract/Free Full Text]
  14. Bertrand ME, Esplugas E, Piessens J, Rasch W. Influence of an ionic, iso-osmolar contrast medium (iodixanol) versus an ionic, low-osmolar contrast medium (ioxaglate) on major adverse cardiac events in patients undergoing percutaneous transluminal coronary angioplasty. A multicenter, randomized, double-blind study. Circulation. 2000;101:131–136[Abstract/Free Full Text]
  15. Davidson CJ, Laskey WK, Hermiller JB. Randomized trial of contrast media utilisation in high-risk PTCA. The COURT trial. Circulation. 2000;101:2172–2177[Abstract/Free Full Text]
  16. Scheller B, Hennen B, Pohl A, Schieffer H, Markwirth T. Acute and subacute stent occlusion: risk-reduction by ionic contrast media. Eur Heart J. 2001;22:385–391[Abstract/Free Full Text]

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