Copyright © 2001 by the European Society of Cardiology.
Editorials
Increased QT dispersion with the D-allele of the ACE polymorphism
Department of Cardiovascular Genetics, University College, London, U.K.
The Rayne Institute, London, U.K.
References
- Campbell RW. ACE inhibitors and arrhythmias. Heart. 1996;76:7982
[Abstract/Free Full Text] - Fletcher RD, Cintron GB, Johnson G, Orndorff J, Carson P, Cohn JN. Enalapril decreases prevalence of ventricular tachycardia in patients with chronic congestive heart failure. The V-HeFT II VA Cooperative Studies Group. Circulation. 1993;87:V149155
- Yusuf, S, Sleight, P, Pogue, J, Bosch, J, Davies, R, Dagenais, G, Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators [see comments] [published erratum appears inN Engl J Med, 2000 Mar 9, 342, 748, N Engl J Med, 2000, 342, 145, 53
- Domanski MJ, Exner DV, Borkowf CB, Geller NL, Rosenberg Y, Pfeffer MA. Effect of angiotensin converting enzyme inhibition on sudden cardiac death in patients following acute myocardial infarction. A meta-analysis of randomized clinical trials. J Am Coll Cardiol. 1999;33:598604
[Abstract/Free Full Text] - Jeron A, Hengstenberg C, Engel S. The D-allele of the ACE polymorphism is related to increased QT dispersion in 609 patients after myocardial infarction. Eur Heart J. 2001;22:663668
[Abstract/Free Full Text] - Danser AH, Schalekamp MA, Bax WA. Angiotensin-converting enzyme in the human heart. Effect of the deletion/insertion polymorphism. Circulation. 1995;92:13871388
[Abstract/Free Full Text] - Elming H, Holm E, Jun L. The prognostic value of the QT interval and QT interval dispersion in all-cause and cardiac mortality and morbidity in a population of Danish citizens. Eur Heart J. 1998;9:13911400
- Ledru F, Blanchard D, Battaglia S. Relation between severity of coronary artery disease, left ventricular function and myocardial infarction, and influence of the ACE I/D gene polymorphism. Am J Cardiol. 1998;82:160165[CrossRef][ISI][Medline]
- Linz W, Wiemer G, Scholkens BA. Beneficial effects of bradykinin on myocardial energy metabolism and infarct size. Am J Cardiol. 1997;80:118A123A[CrossRef][Medline]
- Heusch G, Rose J, Ehring T. Cardioprotection by ACE Inhibitors in Myocardial Ischaemia/Reperfusion. Drugs. 1997;54:3141
- Spargias KS, Lindsay SJ, Hall AS, Cowan JC, Ball SG. Ramipril reduces QT dispersion in patients with acute myocardial infarction and heart failure. Am J Cardiol. 1999;83:969971[CrossRef][ISI][Medline]
- Brown NJ, Blais C, Gandhi SK, Adam A. ACE Insertion/Deletion Genotype Affects Bradykinin Metabolism. J Cardiovasc Pharmacol. 1998;32:373377[CrossRef][ISI][Medline]
- Murphey LJ, Gainer JV, Vaughan DE, Brown NJ. Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin. Circulation. 2000;102:829832
[Abstract/Free Full Text] - Evans AE, Poirier O, Kee F. Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease. Q J Med. 1994;87:211214[ISI][Medline]
- Marian AJ, Yu QT, Workman R, Greve G, Robert R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet. 1993;342:10851086[CrossRef][ISI][Medline]
- Keavney B, McKenzie C, Parish S. Large-scale test of hypothesised associations between the angiotensin- converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators. Lancet. 2000;355:434442[ISI][Medline]
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||