Copyright © 2002 by the European Society of Cardiology.
Prospective evaluation and outcome of patients admitted for syncope over a 1 year period
a Department of Cardiology, Hôpital Universitaire de Brest, Brest, France
b Department of Emergency, Hôpital Universitaire de Brest, Brest, France
revised August 7, 2001; accepted August 15, 2001
Abstract
Aims Syncope is a frequent and potentially dangerous symptom. The epidemiological data are based on series mainly collected 20 years ago in the U.S.A. and do not adequately assist in the management of patients admitted now for this symptom in Europe.
Methods and Results To evaluate prospectively the epidemiological aspects and the management of the patients admitted in the emergency department of an adult university hospital for a verified syncope, charts of all the patients consecutively admitted between June 1999 and June 2000 were systematically reviewed by a member of the cardiology staff. Those with a loss of consciousness were selected and those with a definite syncope were included in the study group and followed until they were discharged from the hospital. Among the 37475 patients who presented to the emergency department, 454 (1·21%) had a definite syncope. For 296 it was the first episode and 169 (mean age 43±23 years) were discharged straight away; 285 (mean age 66±19 years;P <0·0001) were admitted to internal medicine (n=151), cardiology (n=65), neurology (n=44), endocrinology (n=14) and surgery (n=11) services. In 75·7% of all the patients a diagnosis was reported but it was inadequate to explain a syncopal episode in 56 cases (16·3%). Management differed by department: 36% of the patients had neurological investigations mainly in internal medicine and neurology. Except in cardiology very few had cardiological investigations particularly tilt test and electrophysiological studies (5%).
Conclusion Syncope is a frequent symptom but its cause often remains unknown partly due to inadequate management. Precise and simple guidelines are urgently needed.
Key Words: Syncope, epidemiology, diagnosis
f1 Correspondence: Jean-Jacques Blanc, Département de Cardiologie, Hôpital de la Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest Cedex, France.
References
- Kapoor W. Evaluation and outcome of patients with syncope. Medicine. 1990;69:169175
- Kapoor W, Hanusa B. Is syncope a risk factor for poor outcomes? Comparison of patients with and without syncope. Am J Med. 1996;100:645655
- Middlekauff H, Stevenson W, Stevenson L, Saxon L. Syncope in advanced heart failure: high risk of sudden death regardless of origin of syncope. J Am Coll Cardiol. 1993;21:110116[Abstract]
- Kapoor W, Peterson J, Wicand HS, Karpf M. Diagnosis and prognosis implications of recurrences in patients with syncope. Am J Med. 1989;83:700708
- Nyman J, Krahn A, Bland P, Griffiths S, Manda V. The costs of recurrent syncope of unknown origin in elderly patients. PACE. 1999;22:13861394
- Day SC, Cook EF, Funkenstein H, Goldman L. Evaluation and outcome of emergency room patients with transient loss of consciousness. Am J Med. 1982;73:1523[CrossRef][ISI][Medline]
- Kapoor W, Karpf M, Wicand S, Peterson J, Levey G. A prospective evaluation and follow-up of patients with syncope. N Engl J Med. 1983;309:197204[Abstract]
- Silverstein MD, Singer DE, Mulley A, Thibault GE, Barnett GO. Patients with syncope admitted to medical intensive care units. JAMA. 1982;248:11851189[Abstract]
- Savage DD, Corwin L, McGee DL, Kannel WB, Wolf PA. Epidemiologic features of isolated syncope: the Framingham study. Stroke. 1985;16:626629
[Abstract/Free Full Text] - Martin GJ, Adams SL, Martin HG, Matthews J, Zull D, Scanlon PJ. Prospective evaluation of syncope. Ann Emerg Med. 1984;13:499504[CrossRef][ISI][Medline]
- Eagle KA, Black HR, Cook EF, Goldman L. Evaluation of prognostic classifications for patients with syncope. Am J Med. 1985;79:455460[CrossRef][ISI][Medline]
- Ammirati F, Colivicchi F, Santini M. Diagnosing syncope in clinical practice. Implementation of a simplified diagnostic algorithm in a multicenter prospective trial. The OESIL 2 study. Eur Heart J. 2000;21:935940
[Abstract/Free Full Text] - Ammirati F, Colivicchi F, Minardi G. Hospital management of syncope: the OESIL study (osservatonio epidemiologico della sincope nel lazio). G Ital Cardiol. 1999;29:533539[Medline]
- Blanc JJ, Genet L, Forneiro I. Perte de connaissance brève: étiologie et démarche. Résultats d'une étude prospective. Presse Med. 1989;18:923926[ISI][Medline]
- Davis TL, Freemon FR. Electroencephalography should not be routine in the evaluation of syncope in adults. Arch Intern Med. 1990;50:20272029
- Davidson E, Rotenberg Z, Fuchs J, Weinberger I, Agmon J. Transient ischemic attack-related syncope. Clin Cardiol. 1991;14:141144[ISI][Medline]
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