Copyright © 2002 by the European Society of Cardiology.
Left ventricular hypertrophy screening using a hand-held ultrasound device
Department of Cardiology, Thoraxcentre, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
revised December 31, 2001; accepted January 2, 2002
Abstract
Aims To test the diagnostic potential of a hand-held ultrasound device for screening for left ventricular hypertrophy in a hypertensive population using a standard echocardiographic system as a reference.
Methods One hundred consecutive hypertensive patients were enrolled. An experienced investigator performed measurements of the thickness of the anterior septum and posterior wall using the parasternal 2D-long axis view and the end-diastolic dimension of the left ventricle with both imaging devices. Left ventricular hypertrophy was defined as an increase in left ventricular mass
134g.m2 for men and
110g.m2 for women, when indexed for body surface area and
143g.m1 for men and
102g.m1 for women, when indexed for height.
Results Sixty-five men and 35 women were studied (age 60±11 years); mean duration of hypertension: 13±11 years; mean blood pressures: systolic 150±20mmHg and diastolic 89±11mmHg. The anterior septum and posterior wall were visualized in all patients with both imaging devices. The standard echocardiographic system identified left ventricular hypertrophy by body surface area in 18 (18%) patients and by height in 26 (26%) patients. The agreement between the standard echocardiographic system and the hand-held device for the assessment of left ventricular hypertrophy was 93%, kappa: 0·77 (left ventricular mass/body surface area) and 90%, kappa: 0·76 (left ventricular mass/height).
Conclusions We conclude that hand-held devices can be effectively applied for screening for left ventricular hypertrophy in hypertensive patients.
Key Words: Left ventricular hypertrophy, left ventricular mass, hand-held ultrasound device
f1 Correspondence: Don Poldermans, MD, PhD, Thoraxcentre, Room Ba 300, Erasmus Medical Centre Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
References
- Kannel WB, Gordon T, Castelli WP, Margolis JR. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease: the Framingham Study. Ann Intern Med. 1970;72:813822[Medline]
- Kannel WB, Schatzkin A. Sudden death: lessons from subsets in population studies. J Am Coll Cardiol. 1985;5:141B149B[Medline]
- Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med. 1991;114:345352[ISI][Medline]
- Devereux RB, Alderman MH. Role of preclinical cardiovascular disease in the evolution from risk factor exposure to development of morbid events. Circulation. 1993;88:14441455
[Abstract/Free Full Text] - Perlini S, Muiesan ML, Cuspidi C. Midwall mechanics are improved after regression of hypertensive left ventricular hypertrophy and normalization of chamber geometry. Circulation. 2001;6:678683
- Norman JE, Levy D, Campbell G, Bailey JJ. Improved detection of echocardiographic left ventricular hypertrophy using a new electrocardiographic algorithm. J Am Coll Cardiol. 1993;21:16801686[Abstract]
- Molloy T, Okin PM, Devereux RB, Kligfield P. Electrocardiographic detection of left ventricular hypertrophy by the simple QRS voltage-duration product. J Am Coll Cardiol. 1992;20:11801186[Abstract]
- Woythaler JN, Singer SL, Kwan OL. Accuracy of echocardiography versus electrocardiography in detecting left ventricular hypertrophy: comparison with postmortem mass measurements. J Am Coll Cardiol. 1983;2:305311[Abstract]
- Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man: anatomic validation of the method. Circulation. 1977;55:613618
[Abstract/Free Full Text] - Devereux RB, Alonso DR, Lutas EM. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986;57:450458[CrossRef][ISI][Medline]
- Schillaci G, Verdecchia P, Borgioni C, Ciucci A, Guerrieri M, Zampi I. Improved electrocardiographic diagnosis of left ventricular hypertrophy. Am J Cardiol. 1994;74:714719[CrossRef][ISI][Medline]
- Schiller, NB, Shah, PM, Crawford, M, Recommendations for quantitation of the left ventricle by two-dimensional echocardiography, 1989, 2, 358, 67
- Liebson PR, Grandits G, Prineas R. Echocardiographic correlates of left ventricular structure among 844 mildly hypertensive men and women in the treatment of mild hypertension study (TOMHS). Circulation. 1993;87:476486
[Abstract/Free Full Text] - Du Bois D, Du Bois E. A formula to estimate the approximate surface area if height and weight be known. 1916. Nutrition. 1989;5:303311[ISI][Medline]
- Lauer MS, Anderson KM, Levy D. Separate and joint influences of obesity and mild hypertension on left ventricular mass and geometry: the Framingham Heart Study. J Am Coll Cardiol. 1992;19:130134[Abstract]
- Devereux RB, Lutas EM, Casale PN. Standardization of M-Mode echocardiographic left ventricular anatomic measurements. J Am Coll Cardiol. 1984;4:12221230[Abstract]
- Devereux RB, Reichek N. Repolarization abnormalities of left ventricular hypertrophy. Clinical, echocardiographic and hemodynamic correlates. J Electrocardiol. 1982;15:4754[ISI][Medline]
- Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;8:307310
- Fleiss JL. Statistical methods for rates and proportions. New York: Wiley; 1981.
- Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990;322:15611566[Abstract]
- Casale PN, Devereux RB, Milner M. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986;105:173178[ISI][Medline]
- De Simone G, Muiesan ML, Ganau A. Reliability and limitations of echocardiographic measurements of left ventricular mass for risk stratification and follow-up in single patients: The RES trial. Working Group on Heart and Hypertension of the Italian Society of Hypertension. Reliability of M-Mode echocardiographic studies. J Hypertens. 1999;17:19551963[CrossRef][ISI][Medline]
- Palmieri V, Dahlof B, DeQuattro V. Reliability of echocardiographic assessment of left ventricular structure and function; The PRESERVE Study. J Am Coll Cardiol. 1999;34:16251632
[Abstract/Free Full Text] - Vourvouri EC, Poldermans D, De Sutter J, Sozzi FB, Izzo P, Roelandt JRTC. Experience with an ultrasound stethoscope. J Am Soc Echocardiogr. 2002;15:8085[CrossRef][ISI][Medline]
- J Hypertens. 1999;17:151183[ISI][Medline]
- Arch Intern Med. 1997;157:24132446[Abstract]
- De Simone G, Ganau A, Verdecchia P, Devereux RB. Echocardiography in arterial hypertension: when, why and how? J Hypertens. 1994;12:11291136[ISI][Medline]
- De Simone G, Schillaci G, Palmieri V, Devereux RB. Should all patients with hypertension have echocardiography? J Hum Hypertens. 2000;14:417421[CrossRef][ISI][Medline]
- Abergel E, Chatellier G, Battaglia C, Menard J. Can echocardiography identify mildly hypertensive patients at high risk, left untreated based on current guidelines? J Hypertens. 1999;17:817824[CrossRef][ISI][Medline]
- Black HR, Weltin G, Jaffe CC. The limited echocardiogram: a modification of standard echocardiography for use in the routine evaluation of patients with systemic hypertension. Am J Cardiol. 1991;67:10271030[CrossRef][ISI][Medline]
- Sheps SG, Frohlich ED. Limited echocardiography for hypertensive left ventricular hypertrophy. Hypertension. 1997;29:560563
[Free Full Text] - Ganau A, Devereux RB, Roman MJ. Patterns of left ventricular hypertrophy and geometric remodelling in essential hypertension. J Am Coll Cardiol. 1992;19:15501558[Abstract]
- Gopal AS, Keller AM, Shen Z. Three-dimensional echocardiography: in vitro and in vivo validation of left ventricular mass and comparison with conventional echocardiographic methods. J Am Coll Cardiol. 1994;24:504513[Abstract]
- Godkin GM, Spevack DM, Tunick PA, Kronzon I. How useful is hand-carried bedside echocardiography in critically ill patients? J Am Coll Cardiol. 2001;37:20192022
[Abstract/Free Full Text] - Spencer KT, Anderson AS, Bhargava A. Physician-performed point-of-care echocardiography using a laptop platform compared with physical examination in the cardiovascular patient. J Am Coll Cardiol. 2001;37:20132018
[Abstract/Free Full Text] - Schiller NB. Hand-held echocardiography: a revolution or hassle? J Am Coll Cardiol. 2001;37:20232024
[Free Full Text]
This article has been cited by other articles:
![]() |
P Trambaiolo, F Papetti, A Posteraro, E Amici, M Piccoli, E Cerquetani, G Pastena, G Gambelli, and A Salustri A hand-carried cardiac ultrasound device in the outpatient cardiology clinic reduces the need for standard echocardiography Heart, April 1, 2007; 93(4): 470 - 475. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. L. Kobal, S. Atar, and R. J. Siegel Hand-Carried Ultrasound Improves the Bedside Cardiovascular Examination Chest, September 1, 2004; 126(3): 693 - 701. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. L. Kobal, L. S. C. Czer, P. C. Czer, Z. Feldsher, R. Hamilton, and R. J. Siegel Making an Impossible Mission Possible Chest, January 1, 2004; 125(1): 293 - 296. [Abstract] [Full Text] [PDF] |
||||
![]() |
J Quiles, M A Garcia-Fernandez, P B Almeida, E Perez-David, J Bermejo, M Moreno, and P Avanzas Portable spectral Doppler echocardiographic device: overcoming limitations Heart, September 1, 2003; 89(9): 1014 - 1018. [Abstract] [Full Text] [PDF] |
||||
![]() |
A Salustri and P Trambaiolo The "ultrasonic stethoscope": is it of clinical value? Heart, July 1, 2003; 89(7): 704 - 706. [Full Text] [PDF] |
||||
![]() |
E C Vourvouri, L Y Koroleva, F J Ten Cate, D Poldermans, A F L Schinkel, R T van Domburg, W B Vletter, and J R T C Roelandt Clinical utility and cost effectiveness of a personal ultrasound imager for cardiac evaluation during consultation rounds in patients with suspected cardiac disease Heart, July 1, 2003; 89(7): 727 - 730. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Salustri and P. Trambaiolo Point-of-care echocardiography: small, smart and quick Eur. Heart J., October 1, 2002; 23(19): 1484 - 1487. [Full Text] [PDF] |
||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||


