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European Heart Journal 2002 23(24):1938-1945; doi:10.1053/euhj.2002.3286
Copyright © 2002 by the European Society of Cardiology.
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Long-term effects of spinal cord stimulation and coronary artery bypass grafting on quality of life and survival in the ESBY study

O. Ekrea,f1, T. Eliassona, H. Norrsella, P. Währborgb and C. Mannheimera

a Multidisciplinary Pain Center/Östra, Sahlgrenska University Hospital/Östra, Göteborg, Sweden
b Department of Cardiology, Sahlgrenska University Hospital/Östra, Göteborg, Sweden

revised April 20, 2002; accepted April 24, 2002

Abstract

Aims To assess the long-term outcome regarding quality of life and survival in patients who were included in the ESBY study 1992–1995. The ESBY study (Electrical Stimulation versus Coronary Artery Bypass Surgery in Severe Angina Pectoris) included 104 patients—with severe angina, increased surgical risk and no prognostic benefits from revascularization—randomized to coronary artery bypass grafting or spinal cord stimulation.

Methods and Results The ESBY patients' quality of life was analysed using two questionnaires, and 5-year mortality was assessed. Quality of life improved significantly 6 months after spinal cord stimulation and coronary artery bypass grafting, respectively, compared to run-in (P<0·001). The results were consistent after 4·8 years. The 5-year mortality was 27·9%. There were no significant differences between the groups.

Conclusions Spinal cord stimulation as well as coronary artery bypass grafting offered long-lasting improvement in quality of life. Survival up to 5 years was comparable between the groups. Both methods can be considered as effective treatment options for patients with severe angina, increased surgical risks and estimated to have no prognostic benefits from coronary artery bypass grafting. Copyright 2002 The European Society of Cardiology. Published by Elsevier Science Ltd. All rights reserved.

Key Words: Angina, bypass, electrical stimulation, follow-up studies, survival

f1 Correspondence: Dr Olof Ekre, Multidisciplinary Pain Center, Sahlgrenska University Hospital/Östra, S-416 85 Göteborg, Sweden.

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