Skip Navigation

European Heart Journal 1990 11(2):173-181;
Copyright © 1990 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by CARLISLE, E. J. F.
Right arrow Articles by ADGEY, A. A. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CARLISLE, E. J. F.
Right arrow Articles by ADGEY, A. A. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1990 The European Society of Cardiology

Fourier analysis of ventricular fibrillation of varied aetiology

E. J. F. CARLISLE, J. D. ALLEN, W. G. KERNOHAN, J. ANDERSON and A. A. J. ADGEY

Regional Medical Cariology Centre, Royal Victoria Hospital, Departments of Physiology and Orthopadeic Surgery, The Queen's University; and Bio-Medical Engineering Centre, The University of Ulster Belfast, N.Ireland

Received 7 November 1988; revised 1 June 1989; .

Address for Correspondence: Dr. Jennifer Adgey M.D., F.A.C.C.,Regional Medical Cardiology Centre, The Royal Victoria Hospital Grosvenor Road, Belfast, BT 12 6BA. N. Ireland

Abstract

Fast Fourier Transform analysis was used to study ventricular fibrillation induced by several different methods in 43 greyhounds anaesthetized with sodium pentobarbitone. The dominant frequency at the body surface of ventricular fibrillation induced electrically in non-ischaemic hearts was initially 9–9 ±0–7 Hz, remained above 9 Hz for 70 s and then rapidly fell to 5 Hz. The dominant frequency of ventricular fibrillation induced by acute occlusion (initially 12–3 ± 0–2 Hz), or by reperfusion (12–2 + 0–4 Hz) of the anterior descending branch of the left coronary artery, showed a similar time-course. However, ventricular fibrillation induced by administration of potassium (4–8±0–8 Hz) or ouabain (7–1 ± 11 Hz) was significantly slower. Fibrillation recordedfrom the endocardium of the heart initially showed a similar dominant frequency to that recorded at the body surface, but there was no significant fall in frequency over 3–3 mins. There was little difference in the time-course of fibrillation in the non-ischaemic heart recorded directly from the epicardium or from a surface lead.These findings may be of relevance to the poor response to DC countershock after prolonged ventricular fibrillation, hyperkalaemia or cardiac glycosides

Key Words: Ventricular fibrillation • myocardial ischaemia • reperfusion • cardiac glycosides • potassium


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. Patwardhan, S. Moghe, K. Wang, and F. Leonelli
Frequency modulation within electrocardiograms during ventricular fibrillation
Am J Physiol Heart Circ Physiol, August 1, 2000; 279(2): H825 - H835.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
A. Winfree
Electrical turbulence in three-dimensional heart muscle
Science, November 11, 1994; 266(5187): 1003 - 1006.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.