Skip Navigation

European Heart Journal 1992 13(11):1545-1548;
Copyright © 1992 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by ERLEMEIER, H.-H.
Right arrow Articles by BLEIFELD, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ERLEMEIER, H.-H.
Right arrow Articles by BLEIFELD, W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1992 The European Society of Cardiology

Effect of dobutamine on pulmonary gas exchange in patients with severe heart failure

H.-H. ERLEMEIER, W. KUPPER and W. BLEIFELD

Department of Cardiology, University Hospital Eppendorf Hamburg, Germany

Received 8 April 1991; revised 3 January 1992; .

Correspondence: Dr H.-H. Erlemeier, Cardiologist, Ochsenzoller Str, 201, D-2000 Norderstedl, Germany

Abstract

Twenty patients (two female, 18 male, mean age 57±11 years) with severe heart failure NYHA IV (7 coronary artery disease, 13 congestive cardiomyopathy) were treated with 8·8±l·7µg .kg–1. min–1 of dobutamine. Pulmonary gas exchange was analysed by withdrawal of blood samples from a central venous catheter and a radial artery canula.

Dobutamine increased SvO2 from 58·7±11·2% to 72·2±6·3% (P=0·0001) and decreased avDO2 from 7·7±2·45 Vol% to 4·97±1·34 Vol% (P=0·0001). PaO2 and PaCO2 were not changed. Qs/Qt increased slightly from 91±8·3% to 11·3±6·4% (P=0·035). Cardiac index increased by 51% (P=0·0001), pulmonary capillary wedge pressure decreased by 28% (P=0·0001). In patients with severe heart failure, dobutamine improved haemodynamics without detrimental effects on arterial oxygen concentration.

Key Words: Dobutamine • pulmonary gas exchange


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur J Heart FailHome page
C. Opasich, A. Russo, R. Mingrone, M. Zambelli, and L. Tavazzi
Intravenous inotropic agents in the intensive therapy unit: do they really make a difference?
Eur J Heart Fail, March 1, 2000; 2(1): 7 - 11.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.