Copyright © 2000 by the European Society of Cardiology.
A national Survey of Acute Myocardial Infarction and Ischaemia (SAMII) in the U.K.: characteristics, management and in-hospital outcome in women compared to men in patients under 70 years
Cardiac Medicine, National Heart and Lung Institute, Department of Medical Statistics and Evaluation, Royal Postgraduate Medical School, Imperial College of Medicine, London, U.K.
revised March 27, 2000; accepted March 29, 2000
Abstract
Aims To assess the clinical characteristics, management and outcome of women compared to men with acute myocardial infarction or ischaemia.
Design A prospective clinical survey was made in a random sample of 94 District General Hospitals in the U.K. 1064 patients, <70 years of age, comprising six consecutive females and six consecutive males from each hospital, diagnosed on admission as acute coronary syndromes (myocardial infarction or myocardial ischaemia) were studied. Outcome measures included: admission and final diagnosis, time to delivery of care, inpatient management, complications and clinical outcome.
Results Five hundred and three women and 561 men were admitted with a diagnosis of acute myocardial infarction or myocardial ischaemia. Women were older, waited longer between seeking and receiving advice, and much less likely to have infarction than men. After adjustment for age, diagnosis and past medical history there were no gender differences in initial and subsequent hospital management, in complications (recurrent ischaemia, arrhythmias, temporary pacing, heart failure), any routine procedure or outcome. Of all patients, 3·4% died in a District General Hospital, 12·2% were transferred to Specialist Cardiac Centres and 84·4% discharged home. Prophylactic medication on discharge was similar for men and women.
Conclusion After adjustment for age, diagnosis and past medical history, although women waited longer between seeking and receiving medical advice, in hospital their assessment, management, complications, outcome and follow-up arrangements were the same as for men. In hospital, management and outcomes were mainly influenced by age, diagnosis (infarction or ischaemia), a past history of coronary disease, but not by gender. This large, nationally representative, survey has found no evidence of important gender difference in the hospital management of acute ischaemic syndromes.
Key Words: Acute myocardial infarction, myocardial ischaemia, gender differences
f1 Correspondence: Professor D. A. Wood, Cardiac Medicine, National Heart and Lung Institute, Dovehouse Street, London SW3 6LY, U.K.
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