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European Heart Journal 2001 22(8):629-647; doi:10.1053/euhj.2000.2338
Copyright © 2001 by the European Society of Cardiology.
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Reviews

Intracoronary radiation therapy

M.Y Salamea,f1, S Verheyea, I.R Crockerb, N.A.F Chronosa, K.A Robinsona and S.B King, IIIa

a The Andreas Gruentzig Cardiovascular Center, Department of Medicine (Cardiology), Emory University School of Medicine, Atlanta, GA, U.S.A.
b Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, U.S.A.

Received September 21, 2000; accepted October 5, 2000

Key Words: Restenosis • radiation • brachythreapy • angioplasty • thrombosis

f1 Correspondence: M. Y. Salame, BSc, MB BS, MRCP, Fellow in Clinical Interventional Cardiology & Intracoronary Irradiation Research, The Andreas Gruentzig Cardiovascular Center, Suite F606, Emory University Hospital, 1364 Clifton Road, N.E., Atlanta, Georgia, U.S.A.

References

  1. Holmes DRJ, Vlietstra RE, Smith HC. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): a report from the PTCA Registry of the National Heart, Lung, and Blood Institute. Am J Cardiol. 1984;53:77C–81C[CrossRef][Medline]
  2. Klein LW, Rosenblum J. Restenosis after successful percutaneous transluminal coronary angioplasty. Progr Cardiovasc Dis. 1990;32:365–382[CrossRef][Web of Science][Medline]
  3. Hong MK, Mehran R, Mintz GS, Leon MB. Restenosis after coronary angioplasty. Curr Probl Cardiol. 1997;22:1–36[CrossRef][Medline]
  4. Thornton MA, Gruentzig AR, Hollman J, King SB, Douglas JS. Coumadin and aspirin in prevention of recurrence after transluminal coronary angioplasty: a randomized study. Circulation. 1984;69:721–727[Abstract/Free Full Text]
  5. Ellis SG, Roubin GS, Wilentz J, Douglas JSJ, King SB. Effect of 18- to 24-hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty. Am Heart J. 1989;117:777–782[CrossRef][Web of Science][Medline]
  6. Schwartz L, Bourassa MG, Lesperance J. Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty. N Engl J Med. 1988;318:1714–1719[Abstract]
  7. Whitworth HB, Roubin GS, Hollman J. Effect of nifedipine on recurrent stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1986;8:1271–1276[Abstract]
  8. Corcos T, David PR, Val PG. Failure of diltiazem to prevent restenosis after percutaneous transluminal coronary angioplasty. Am Heart J. 1985;109:926–931[CrossRef][Web of Science][Medline]
  9. Weintraub WS, Boccuzzi SJ, Klein JL. Lack of effect of lovastatin on restenosis after coronary angioplasty. Lovastatin Restenosis Trial Study Group. N Engl J Med. 1994;331:1331–1337[Abstract/Free Full Text]
  10. Dehmer GJ, Popma JJ, van den Berg EK. Reduction in the rate of early restenosis after coronary angioplasty by a diet supplemented with n-3 fatty acids. N Engl J Med. 1988;319:733–740[Abstract]
  11. Reis GJ, Boucher TM, Sipperly ME. Randomised trial of fish oil for prevention of restenosis after coronary angioplasty. Lancet. 1989;2:177–181[CrossRef][Web of Science][Medline]
  12. Circulation. 1992;86:100–110[Abstract/Free Full Text]
  13. Desmet W, Vrolix M, De SI, Van Lierde J, Willems JL, Piessens J. Angiotensin-converting enzyme inhibition with fosinopril sodium in the prevention of restenosis after coronary angioplasty. Circulation. 1994;89:385–392[Abstract/Free Full Text]
  14. Faxon DP, Spiro TE, Minor S. Low molecular weight heparin in prevention of restenosis after angioplasty. Results of Enoxaparin Restenosis (ERA) Trial. Circulation. 1994;90:908–914[Abstract/Free Full Text]
  15. Serruys PW, Klein W, Tijssen JP. Evaluation of ketanserin in the prevention of restenosis after percutaneous transluminal coronary angioplasty. A multicenter randomized double-blind placebo-controlled trial. Circulation. 1993;88:1588–1601[Abstract/Free Full Text]
  16. Emanuelsson H, Beatt KJ, Bagger JP. Long-term effects of angiopeptin treatment in coronary angioplasty. Reduction of clinical events but not angiographic restenosis. European Angiopeptin Study Group. Circulation. 1995;91:1689–1696[Abstract/Free Full Text]
  17. Franklin SM, Faxon DP. Pharmacologic prevention of restenosis after coronary angioplasty: review of the randomized clinical trials. Cor Art Dis. 1993;4:232–242
  18. Kuntz RE, Gibson CM, Nobuyoshi M, Baim DS. Generalized model of restenosis after conventional balloon angioplasty, stenting and directional atherectomy. J Am Coll Cardiol. 1993;21:15–25[Abstract]
  19. Wong CS, Leon MB, Popma JJ. New device angioplasty: the impact on restenosis. Cor Art Dis. 1993;4:243–253
  20. Waksman R, Popma JJ, Kennard ED. Directional coronary atherectomy (DCA): a report from the New Approaches to Coronary Intervention (NACI) registry. Am J Cardiol. 1997;80:50K–59K[CrossRef][Web of Science][Medline]
  21. Brown DL, George CJ, Steenkiste AR. High-speed rotational atherectomy of human coronary stenoses: acute and one-year outcomes from the New Approaches to Coronary Intervention (NACI) registry. Am J Cardiol. 1997;80:60K–67K[CrossRef][Web of Science][Medline]
  22. Holmes DRJ, Mehta S, George CJ. Excimer laser coronary angioplasty: the New Approaches to Coronary Intervention (NACI) experience. Am J Cardiol. 1997;80:99K–105K[CrossRef][Web of Science][Medline]
  23. Safian RD, Freed M, Reddy V. Do excimer laser angioplasty and rotational atherectomy facilitate balloon angioplasty? Implications for lesion-specific coronary intervention. J Am Coll Cardiol. 1996;27:552–559[Abstract]
  24. Henson KD, Flood R, Javier SP. Transcatheter device synergy: use of adjunct directional atherectomy after rotational atherectomy or excimer laser angioplasty (Abstr). J Am Coll Cardiol. 1994;:220A
  25. Topol EJ, Leya F, Pinkerton CA. A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. The CAVEAT Study Group. N Engl J Med. 1993;329:221–227[Abstract/Free Full Text]
  26. Adelman AG, Cohen EA, Kimball BP. A comparison of directional atherectomy with balloon angioplasty for lesions of the left anterior descending coronary artery. N Engl J Med. 1993;329:228–233[Abstract/Free Full Text]
  27. Bittl JA, Kuntz RE, Estella P, Sanborn TA, Baim DS. Analysis of late lumen narrowing after excimer laser-facilitated coronary angioplasty. J Am Coll Cardiol. 1994;23:1314–1320[Abstract]
  28. Reifart N, Vandormael M, Krajcar M. Randomized comparison of angioplasty of complex coronary lesions at a single center. Excimer Laser, Rotational Atherectomy, and Balloon Angioplasty Comparison (ERBAC) Study. Circulation. 1997;96:91–98[Abstract/Free Full Text]
  29. Fischman DL, Leon MB, Baim DS. A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. Stent Restenosis Study Investigators. N Engl J Med. 1994;331:496–501[Abstract/Free Full Text]
  30. Serruys PW, de Jaegere P, Kiemeneij F. A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group. N Engl J Med. 1994;331:489–495[Abstract/Free Full Text]
  31. Dussaillant GR, Mintz GS, Pichard AD. Small stent size and intimal hyperplasia contribute to restenosis: a volumetric intravascular ultrasound analysis. J Am Coll Cardiol. 1995;26:720–724[Abstract]
  32. Elezi S, Kastrati A, Neumann FJ, Hadamitzky M, Dirschinger J, Schomig A. Vessel size and long-term outcome after coronary stent placement. Circulation. 1998;98:1875–1880[Abstract/Free Full Text]
  33. Mintz GS, Hoffmann R, Mehran R. In-stent restenosis: the Washington Hospital Center experience. Am J Cardiol. 1998;81:7E–13E[CrossRef][Web of Science][Medline]
  34. King SB. Intravascular radiation for restenosis prevention: could it be the holy grail? Heart. 1996;76:99–100[Free Full Text]
  35. Waksman R. Local catheter-based intracoronary radiation therapy for restenosis. Am J Cardiol. 1996;78:23–28[CrossRef][Web of Science][Medline]
  36. Waksman R. Vascular Brachytherapy. Armonk, New York: Futura Publishing Co., Inc; 1999.
  37. Condado JA, Waksman R, Gurdiel O. Long-term angiographic and clinical outcome after percutaneous transluminal coronary angioplasty and intracoronary radiation therapy in humans. Circulation. 1997;96:727–732[Abstract/Free Full Text]
  38. Verin V, Urban P, Popowski Y. Feasibility of intracoronary beta-irradiation to reduce restenosis after balloon angioplasty. A clinical pilot study. Circulation. 1997;95:1138–1144[Abstract/Free Full Text]
  39. Teirstein PS, Massullo V, Jani S. Catheter-based radiotherapy to inhibit restenosis after coronary stenting. N Engl J Med. 1997;336:1697–1703[Abstract/Free Full Text]
  40. King SB, Williams DO, Chougule P. Endovascular beta-radiation to reduce restenosis after coronary balloon angioplasty: results of the beta energy restenosis trial (BERT). Circulation. 1998;97:2025–2030[Abstract/Free Full Text]
  41. Essed CE, Van den Brand, Becker AE. Transluminal coronary angioplasty and early restenosis. Fibrocellular occlusion after wall laceration. Br Heart J. 1983;49:393–396[Abstract/Free Full Text]
  42. Austin GE, Ratliff NB, Hollman J, Tabei S, Phillips DF. Intimal proliferation of smooth muscle cells as an explanation for recurrent coronary artery stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1985;6:369–375[Abstract]
  43. Liu MW, Roubin GS, King SB. Restenosis after coronary angioplasty. Potential biologic determinants and role of intimal hyperplasia. Circulation. 1989;79:1374–1387[Abstract/Free Full Text]
  44. Gravanis MB, Roubin GS. Histopathologic phenomena at the site of percutaneous transluminal coronary angioplasty: the problem of restenosis. Hum Pathol. 1989;20:477–485[CrossRef][Web of Science][Medline]
  45. Waller BF, Pinkerton CA, Orr CM, Slack JD, VanTassel JW, Peters T. Restenosis 1 to 24 months after clinically successful coronary balloon angioplasty: a necropsy study of 20 patients. J Am Coll Cardiol. 1991;17:58B–70B[Medline]
  46. Pickering JG, Weir L, Jekanowski J, Kearney MA, Isner JM. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest. 1993;91:1469–1480[Web of Science][Medline]
  47. Gravanis MB, Robinson KA, Santoian EC, Schneider JE, King SB III. The reparative phenomena at the site of balloon angioplasty in human and experimental models. Cardiovasc Pathol. 1993;2:263–273
  48. Komatsu R, Ueda M, Naruko T, Kojima A, Becker AE. Neointimal tissue response at sites of coronary stenting in humans: macroscopic, histological, and immunohistochemical analyses. Circulation. 1998;98:224–233[Abstract/Free Full Text]
  49. Kearney M, Pieczek A, Haley L. Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation. 1997;95:1998–2002[Abstract/Free Full Text]
  50. Prasad KN. Radiation response of human tumors. Prasad KN. Handbook of Radiobiology. Boca Raton: CRC Press; 1995. p. 305–315
  51. Baensch W. Ueber die Strahlentherapie der Keloide. Strahlentherapie. 1937;60:204–209
  52. Doornbos JF, Stoffel TJ, Hass AC. The role of kilovoltage irradiation in the treatment of keloids. Int J Rad Oncol Biol Phys. 1990;18:833–839[Web of Science][Medline]
  53. Sallstrom KO, Larson O, Heden P, Eriksson G, Glas JE, Ringborg U. Treatment of keloids with surgical excision and postoperative X-ray radiation. Scand J Plast Reconstr Surg Hand Surg. 1989;23:211–215[Web of Science][Medline]
  54. Lo TC, Healy WL, Covall DJ. Heterotopic bone formation after hip surgery: prevention with single-dose postoperative hip irradiation. Radiology. 1988;168:851–854[Abstract/Free Full Text]
  55. Anthony P, Keys H, Evarts CM, Rubin P, Lush C. Prevention of heterotopic bone formation with early post operative irradiation in high risk patients undergoing total hip arthroplasty: comparison of 10.00 Gy vs 20.00 Gy schedules. Int J Rad Oncol Biol Phys. 1987;13:365–369[Web of Science][Medline]
  56. Paryani SB, Scott WP, Wells JWJ. Management of pterygium with surgery and radiation therapy. The North Florida Pterygium Study Group. Int J Rad Oncol Biol Phys. 1994;28:101–103[Web of Science][Medline]
  57. Bahrassa F, Datta R. Postoperative beta radiation treatment of pterygium. Int J Rad Oncol Biol Phys. 1983;9:679–684[Web of Science][Medline]
  58. Sinclair WK. Cyclic x-ray responses in mammalian cells in vitro. Rad Res. 1968;33:620–643[Web of Science][Medline]
  59. Fischer-Dzoga K, Dimitrievich GS, Griem ML. Radiosensitivity of vascular tissue. II. Differential radiosensitivity of aortic cells in vitro. Rad Res. 1984;99:536–546[CrossRef][Web of Science][Medline]
  60. Fischer-Dzoga K, Dimitrievich GS, Schaffner T. Effect of hyperlipidemic serum and irradiation on wound healing in primary quiescent cultures of vascular cells. Exper Molec Pathol. 1990;52:1–12
  61. Rosen EM, Goldberg ID, Myrick KV, Levenson S. Radiation survival properties of cultured vascular smooth muscle cells. Rad Res. 1984;100:182–191[CrossRef][Web of Science][Medline]
  62. Chan HP, Doi K. The validity of Monte Carlo simulation in studies of scattered radiation in diagnostic radiology. Phys Med Biol. 1983;28:109–129[CrossRef][Web of Science][Medline]
  63. Webb S, Parker RP. A Monte Carlo study of the interaction of external beam X-radiation with inhomogeneous media. Phys Med Biol. 1978;23:1043–1059[CrossRef][Web of Science][Medline]
  64. Green MV, Aamodt RL, Johnston GS. Monte Carlo calculation of the absolute maximum detection efficiency of a cylindrical gamma radiation detector. Health Phys. 1975;28:624–628[Web of Science][Medline]
  65. Hall EJ, Miller RC, Brenner DJ. The basic radiobiology of intravascular irradiation. Waksman R. Vascular Brachytherapy. Armonk: Futura Publishing Co., Inc; 1999. p. 63–72
  66. Illidge TM. Radiation-induced apoptosis. Clin Oncol. 1998;10:3–13
  67. Harms-Ringdahl M, Nicotera P, Radford IR. Radiation induced apoptosis. Mutat Res. 1996;366:171–179[CrossRef][Web of Science][Medline]
  68. Dewey WC, Ling CC, Meyn RE. Radiation-induced apoptosis: relevance to radiotherapy. Int J Rad Oncol Biol Phys. 1995;33:781–796[CrossRef][Web of Science][Medline]
  69. Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 1972;26:239–257[Web of Science][Medline]
  70. Waksman R, Rodriguez JC, Robinson KA. Effect of intravascular irradiation on cell proliferation, apoptosis, and vascular remodeling after balloon overstretch injury of porcine coronary arteries. Circulation. 1997;96:1944–1952[Abstract/Free Full Text]
  71. Hehrlein C. Radioactive stents. Waksman R. Vascular Brachytherapy. Armonk: Futura Publishing Co., Inc; 1999. p. 333–342
  72. Vodovotz Y, Chan RC, Bhargava B, Collins SD, Waksman, R. Intracoronary radiation increases apoptosis at 14 days in porcine coronary arteries. Cardiovasc Rad Ther III Washington, DC. 1999;:45
  73. Popowski Y, Verin V, Papirov I. Intra-arterial 90Y brachytherapy: preliminary dosimetric study using a specially modified angioplasty balloon. Int J Rad Oncol Biol Phys. 1995;33:713–717[CrossRef][Web of Science][Medline]
  74. Scott NA. The soft X-ray catheter system. Cardiovasc Rad Ther III Washington, DC. 1999;:410–413
  75. Inalsingh CH. An experience in treating five hundred and one patients with keloids. Johns Hopkins Med J. 1974;134:284–290[Web of Science][Medline]
  76. Borok TL, Bray M, Sinclair I, Plafker J, LaBirth L, Rollins C. Role of ionizing irradiation for 393 keloids. Int J Rad Oncol Biol Phys. 1988;15:865–870[Web of Science][Medline]
  77. Amols HI, Zaider M, Weinberger J, Ennis R, Schiff PB, Reinstein LE. Dosimetric considerations for catheter-based beta and gamma emitters in the therapy of neointimal hyperplasia in human coronary arteries. Int J Rad Oncol Biol Phys. 1996;36:921
  78. Amols HI, Reinstein LE, Weinberger J. Dosimetry of a radioactive coronary balloon dilitation catheter for treatment of neointimal hyperplasia. Med Phys. 1996;23:1788
  79. Amols HI. Intravascular brachytherapy physics: review of radiation sources and techniques. Waksman R. Vascular brachytherapy. Armonk: Futura Publishing Co., Inc; 1999. p. 177–190
  80. Loevinger R. Distribution of absorbed energy around a point source of beta radiation. Science. 1950;112:530–531[Free Full Text]
  81. Robinson KA, Pipes DW, Van Bibber R. 186Re-Liquid-filled balloon catheter system for endovascular brachytherapy: dose-response efficacy study and biodistribution after coronary injection (Abstr). Circulation. 1998;98:I-653
  82. Trauthen B, Buchbinder M, Tam L. Intracoronary beta radiation after stent implantation in a porcine model. Cardiovasc Rad Ther III Washington, DC. 1999;:39
  83. Strathearn G, Trauthen B, Tam L. Extraction of isotope from a radiance RDX balloon encapsulated thin film source in an arterial flow model. Cardiovasc Rad Ther III Washington, DC. 1999;:41
  84. Fischell, RE, Fischell, TA, Intra-arterial stent with capability to inhibit internal hyperplasia, 1989
  85. Fischell TA, Kharma BK, Fischell DR. Low-dose, beta-particle emission from ‘stent’ wire results in complete, localized inhibition of smooth muscle cell proliferation. Circulation. 1994;90:2956–2963[Abstract/Free Full Text]
  86. Hafeli UO, Warburton MC, Landau U. Electrodeposition of radioactive rhenium onto stents to prevent restenosis. Biomaterials. 1998;19:925–933[CrossRef][Web of Science][Medline]
  87. Hehrlein C, Gollan C, Donges K. Low-dose radioactive endovascular stents prevent smooth muscle cell proliferation and neointimal hyperplasia in rabbits. Circulation. 1995;92:1570–1575[Abstract/Free Full Text]
  88. Hehrlein C, Stintz M, Kinscherf R. Pure beta-particle-emitting stents inhibit neointima formation in rabbits. Circulation. 1996;93:641–645[Abstract/Free Full Text]
  89. Janicki C, Duggan DM, Coffey CW, Fischell DR, Fischell TA. Radiation dose from a phosphorous-32 impregnated wire mesh vascular stent. Med Phys. 1997;24:437–445[CrossRef][Web of Science][Medline]
  90. Li AN, Eigler NL, Litvack F, Whiting JS. Characterization of a positron emitting V48 nitinol stent for intracoronary brachytherapy. Med Phys. 1998;25:20–28[CrossRef][Web of Science][Medline]
  91. Duggan DM, Coffey CW, Levit S. Dose distribution for a 32P-impregnated coronary stent: comparison of theoretical calculations and measurements with radiochromic film. Int J Rad Oncol Biol Phys. 1998;40:713–720[CrossRef][Web of Science][Medline]
  92. Prestwich WV. Analytic representation of the dose from a 32P-coated stent. Med Phys. 1996;23:9–13[CrossRef][Web of Science][Medline]
  93. Prestwich WV, Kennett TJ, Kus FW. The dose distribution produced by a 32P-coated stent. Med Phys. 1995;22:313–320[CrossRef][Web of Science][Medline]
  94. Friedman M, Felton L, Byers S. The antiatherogenic effect of Iridium192 upon the cholesterol-fed rabbit. J Clin Invest. 1964;43:185–192[Web of Science][Medline]
  95. Abbas MA, Afshari NA, Stadius ML, Kernoff RS, Fischell TA. External beam irradiation inhibits neointimal hyperplasia following balloon angioplasty. Int J Cardiol. 1994;44:191–202[CrossRef][Web of Science][Medline]
  96. Hehrlein C, Kaiser S, Kollum M, Kinscherf R, Metz J, Fritz P. External beam radiation fails to inhibit neointima formation in stented rabbit arteries (Abstr). Circulation. 1996;94:I-210
  97. Sarac TP, Riggs PN, Williams JP. The effects of low-dose radiation on neointimal hyperplasia. J Vasc Surg. 1995;22:17–24[CrossRef][Web of Science][Medline]
  98. Schwartz RS, Koval TM, Edwards WD. Effect of external beam irradiation on neointimal hyperplasia after experimental coronary artery injury. J Am Coll Cardiol. 1992;19:1106–1113[Abstract]
  99. Shimotakahara S, Mayberg MR. Gamma irradiation inhibits neointimal hyperplasia in rats after arterial injury. Stroke. 1994;25:424–428[Abstract]
  100. Gellman G, Healey G, Qingsheng C. The effect of very low dose irradiation on restenosis following balloon angioplasty. A study in the atherosclerotic rabbit. Circulation. 1991;84:46A–59A
  101. Hirai T, Korogi Y, Harada M, Takashashi M. Intimal hyperplasia in an atherosclerotic model: prevention with radiation therapy (Abstr). Radiology. 1994;:872
  102. Schefer A, Eigler NL, Whiting JS, Litvack FI. Suppression of intimal proliferation with balloon angioplasty with local beta irradiation in rabbits. J Am Coll Cardiol. 1993;21:185A
  103. Robinson KA, Verheye S, Salame MY. External radiation for restenosis. J Intervent Cardiol. 1999;12:235–241
  104. Verheye S, Robinson KA, Cui J. External beam irradiation reduces neointima formation and augments lumen size after coronary stenting in pigs (Abstr). J Am Coll Cardiol. 1999;33:57A
  105. Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary irradiation markedly reduces restenosis after balloon angioplasty in a porcine model. J Am Coll Cardiol. 1994;23:1491–1498[Abstract]
  106. Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary irradiation markedly reduces neointimal proliferation after balloon angioplasty in swine: persistent benefit at 6-month follow-up. J Am Coll Cardiol. 1995;25:1451–1456[Abstract]
  107. Waksman R, Robinson KA, Crocker IR, Gravanis MB, Cipolla GD, King SB. Endovascular low-dose irradiation inhibits neointima formation after coronary artery balloon injury in swine. A possible role for radiation therapy in restenosis prevention. Circulation. 1995;91:1533–1539[Abstract/Free Full Text]
  108. Weinberger J, Amols H, Ennis RD, Schwartz A, Wiedermann JG, Marboe C. Intracoronary irradiation: dose response for the prevention of restenosis in swine. Int J Rad Oncol Biol Phys. 1996;36:767–775[CrossRef][Web of Science][Medline]
  109. Mazur W, Ali MN, Khan MM. High dose rate intracoronary radiation for inhibition of neointimal formation in the stented and balloon-injured porcine models of restenosis: angiographic, morphometric, and histopathologic analyses. Int J Rad Oncol Biol Phys. 1996;36:777–788[CrossRef][Web of Science][Medline]
  110. Waksman R, Robinson KA, Crocker IR. Intracoronary radiation before stent implantation inhibits neointima formation in stented porcine coronary arteries. Circulation. 1995;92:1383–1386[Abstract/Free Full Text]
  111. Verin V, Popowski Y, Urban P. Intraarterial beta irradiation prevents neointimal hyperplasia in a hypercholesterolemic rabbit restenosis model (Abstr). J Am Coll Cardiol. 1995;:2A
  112. Verin V, Popowski Y, Urban P. Intra-arterial beta irradiation prevents neointimal hyperplasia in a hypercholesterolemic rabbit restenosis model. Circulation. 1995;92:2284–2290[Abstract/Free Full Text]
  113. Waksman R, Robinson KA, Crocker IR. Intracoronary low-dose beta-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model. Circulation. 1995;92:3025–3031[Abstract/Free Full Text]
  114. Makkar R, Whiting JS, Honda H. Inhibition of stent restenosis by beta-emitting Rhenium-188 balloon is dose-dependent and injury-dependent (Abstr). Circulation. 1998;98:I-779
  115. Raizner AE, Mazur W, Ali MN. Endovascular radiation with beta and gamma sources in the porcine model. Waksman R. Vascular brachytherapy. Armonk: Futura Publishing Co., Inc; 1999. p. 287–296
  116. Gieldd KN, Amols H, Marboe CC. Effectiveness of a beta emitting liquid-filled perfusion balloon to prevent restenosis (Abstr). Circulation. 1997;96:I-220
  117. Raizner AE, Calfee RV. The Guidant intravascular brachytherapy system. Waksman R, Serruys PW. Handbook of vascular brachytherapy. London: Martin Dunitz; 1998. p. 53–58
  118. Eigler NL, Whiting JS, Makkar R. Radiant liquid isotope intravascular radiation system. Cardiovasc Rad Ther II Washington, DC. 1998;:234–237
  119. Honda H, Hausleiter J, Li A, Makkar R, Whiting J, Eigler N. Edge stenosis after ‘low dose’ radiation therapy using a Re188 liquid-filled balloon system. Cardiovasc Rad Ther III Washington, DC. 1999;:30
  120. Waksman R. Endovascular beta radiation in the swine model. Waksman R. Vascular brachytherapy. Armonk: Futura Publishing Co., Inc; 1999. p. 273–286
  121. Bhargava B, Chan RC, Kim WH, Vodovotz Y, Waksman R. Inhibition of neointima formation in porcine coronary arteries by Rhenium-186/188 radioactive coil delivered intracoronary after balloon injury. Cardiovasc Rad Ther III Washington, DC. 1999;:27
  122. Waksman R, Chan RC, Kim WH, Vodovotz Y, Lavie E. Intracoronary delivery of Rhenium-186 radioactive coil after balloon injury inhibits neointima formation in swine coronary arteries (Abstr). Circulation. 1998;98:I-557
  123. Laird JR, Carter AJ, Kufs WM. Inhibition of neointimal proliferation with low-dose irradiation from a beta-particle-emitting stent. Circulation. 1996;93:529–536[Abstract/Free Full Text]
  124. Carter AJ, Laird JR, Bailey LR. Effects of endovascular radiation from a beta-particle-emitting stent in a porcine coronary restenosis model. A dose-response study. Circulation. 1996;94:2364–2368[Abstract/Free Full Text]
  125. Rivard A, Leclerc G, Bouchard M. Low-dose beta-emitting radioactive stents inhibit neointimal hyperplasia in porcine coronary arteries: an IVUS assessment (Abstr). Circulation. 1996;94:I-210
  126. Farb A, Tang AL, Virmani R. Neointima is reduced but endothelialization is incomplete 3 months after 32P beta-emitting stent placement (Abstr). Circulation. 1998;98:I-779
  127. Carter AJ. Long-term results in animals with the radioactive stent. Cardiovascular radiation therapy III Washington, DC. 1999;:174–177
  128. Fajardo LF, Stewart JR. Experimental radiation-induced heart disease. I. Light microscopic studies. Am J Pathol. 1970;59:299–316[Web of Science][Medline]
  129. Marijianowski MMH, Robinson K, Crocker IR. Comparison of endovascular and external beam irradiation in the prevention of restenosis. Waksman R. Vascular Brachytherapy. Armond: Futura Publishing Co., Inc; 1999. p. 221–230
  130. Wiedermann JG, Leavy JA, Amols H. Effects of high-dose intracoronary irradiation on vasomotor function and smooth muscle histopathology. Am J Physiol. 1994;267:H125–H132
  131. Salame MY, Verheye S, Lampkin J. Effects of endovascular irradiation on platelet recruitment in balloon-injured coronary arteries (Abstr). Eur Heart J. 1999;:138
  132. Vodovotz Y, Bhargava B, Collins SD, Chan RC, Waksman R. Endovascular radiation increases thrombosis rate with decreased luminal thrombi and thrombus area (Abstr). Cardiovasc Rad Ther III Washington, DC. 1999;:38
  133. Raizner AE. Six-month studies with the P32. Cardiovasc Rad Ther III Washington, DC. 1999;:178
  134. Taylor AJ, Gorman PD, Farb A, Hoopes TG, Sweet W, Virmani R. Differential effect of 32P beta particle-emitting stents on the neointima and adventitia in the dog model (Abstr). Circulation. 1998;98:I-779
  135. Liermann D, Bottcher HD, Kollath J. Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries. Cardiovasc Intervent Radiol. 1994;17:12–16[CrossRef][Web of Science][Medline]
  136. Condado JA, Lansky AJ, Saucedo JF. Three year clinical and angiographic follow-up after intracoronary 192-Iridium radiation therapy (Abstr). Circulation. 1998;98:I-651
  137. Teirstein PS, Massullo V, Jani S. Two-year follow-up after catheter-based radiotherapy to inhibit coronary restenosis. Circulation. 1999;99:243–247[Abstract/Free Full Text]
  138. Teirstein PS, Massullo V, Jani S. Radiotherapy to reduce restenosis: subgroup analysis of the SCRIPPS randomized trial (Abstr). Circulation. 1997;96:I-218
  139. Waksman R, White LR, Chan RC. Intracoronary radiation therapy for patients with in-stent restenosis: 6 month follow-up of a randomized clinical study (Abstr). Circulation. 1998;98:I-651
  140. Waksman R, Porrazo MS, Chan RC. Results from the ARTISTIC feasibility study of 192-Iridium gamma radiation to prevent recurrence of in-stent restenosis (Abstr). Circulation. 1998;98:I-442
  141. Hirshfeld JWJ, Schwartz JS, Jugo R. Restenosis after coronary angioplasty: a multivariate statistical model to relate lesion and procedure variables to restenosis. The M-HEART Investigators. J Am Coll Cardiol. 1991;18:647–656[Abstract]
  142. Ellis SG, Roubin GS, King SB, Douglas JSJ, Cox WR. Importance of stenosis morphology in the estimation of restenosis risk after elective percutaneous transluminal coronary angioplasty. Am J Cardiol. 1989;63:30–34[CrossRef][Web of Science][Medline]
  143. Leimgruber PP, Roubin GS, Hollman J. Restenosis after successful coronary angioplasty in patients with single-vessel disease. Circulation. 1986;73:710–717[Abstract/Free Full Text]
  144. Akiyama T, Moussa I, Reimers B. Angiographic and clinical outcome following coronary stenting of small vessels: a comparison with coronary stenting of large vessels. J Am Coll Cardiol. 1998;32:1610–1618[Abstract/Free Full Text]
  145. Mews GC, Fox R, Cope G, Clugston R, Cumpston GC, Gibbons F. Rhenium 188 liquid filled balloon for the treatment of intracoronary instent restenosis: A 26 patient pilot study (Abstr). Cardiovasc Rad Ther III Washington, DC. 1999;:23
  146. Raizner AE, Oesterle S, Waksman R. The PREVENT trial, a feasibility study of intracoronary brachytherapy in the prevention of restenosis: an interim report (Abstr). Circulation. 1998;98:I-651
  147. Baim DS, Fischell TA, Weissman NJ, Laird JR, Marble SJ, Ho KK. Short-term (1 month) results of the IRIS feasibility study of a beta-particle emitting radioisotope stent (Abstr). Circulation. 1997;96:I-218
  148. Moses JW, Ellis SG, Bailey SR. Short-term (1 month) results of the dose response IRIS feasibility study of a beta-particle emitting radioisotope stent (Abstr). J Am Coll Cardiol. 1998;31:350A
  149. Hehrlein C, Brachmann J, Hardt S. P-32 stents for prevention of restenosis: results of the Heidelberg safety trial using the Palmaz-Schatz stent design at moderate activity levels in patients with restenosis after PTCA (Abstr). Circulation. 1998;98:I-780
  150. Albiero R, Di Mario C, De Gregorio J, Kobayashi N, Adamian M, Moussa I. Intravascular ultrasound (IVUS) analysis of beta-particle emitting radioactive stent implantation in human coronary arteries. Preliminary immediate and intermediate-term results of the MILAN study (Abstr). Circulation. 1998;98:I-780
  151. Albiero R, Wardeh AJ, Di Mario C. Acute and 30 days results of 32-P beta-particle emitting radioactive stent implantation in patients with CAD—The European experience (Abstr). Circulation. 1998;98:I-778
  152. Albiero R, Adamian M, De Gregorio J. Results of the Milan BX doseresponse study on 22-P radioactive beta-emitting stent implantation in patients with CAD. Cardiovasc Rad Ther III Washington, DC. 1999;:391–392
  153. Hoffmann R, Mintz GS, Dussaillant GR. Patterns and mechanisms of in-stent restenosis. A serial intravascular ultrasound study. Circulation. 1996;94:1247–1254[Abstract/Free Full Text]
  154. Fajardo LF, Berthrong M. Vascular lesions following radiation. Pathol Ann. 1988;23:297–330
  155. Fajardo LF. Radiation-induced coronary artery disease. Chest. 1977;71:563–564[Free Full Text]
  156. Fajardo LF, Lee A. Rupture of major vessels after radiation. Cancer. 1975;36:904–913[CrossRef][Web of Science][Medline]
  157. Conomy JP, Kellermeyer RW. Delayed cerebrovascular consequences of therapeutic radiation. A clinicopathologic study of a stroke associated with radiation-related carotid arteriopathy. Cancer. 1975;36:1702–1708[CrossRef][Web of Science][Medline]
  158. Suzuki K. Multistep nature of X-ray-induced neoplastic transformation in mammalian cells: genetic alterations and instability. J Rad Res. 1997;38:55–63
  159. Rosen IB, Simpson JA, Sutcliffe S, Gorenstein L. High-dose radiation and the emergence of thyroid nodular disease. Surg. 1984;96:988–995
  160. Waga S, Handa H. Radiation-induced meningioma: with review of literature. Surg Neurol. 1976;5:215–219[Medline]
  161. Karlsson P, Holmberg E, Samuelsson A, Johansson KA, Wallgren A. Soft tissue sarcoma after treatment for breast cancer-a Swedish population-based study. Eur J Cancer. 1998;34:2068–2075[CrossRef][Web of Science][Medline]
  162. Karlsson P, Holmberg E, Johansson KA, Kindblom LG, Carstensen J, Wallgren A. Soft tissue sarcoma after treatment for breast cancer. Radiother Oncol. 1996;38:25–31[CrossRef][Web of Science][Medline]
  163. Popowski, Y. Can vascular radiotherapy induce carcinogenesis? Cardiovasc Rad Ther III Washington, DC. 1999;:195–196
  164. Rodriguez AE, Santaera O, Larribau M. Coronary stenting decreases restenosis in lesions with early loss in luminal diameter 24 hours after successful PTCA. Circulation. 1995;91:1397–1402[Abstract/Free Full Text]

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