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European Heart Journal 2003 24(19):1703-1704; doi:10.1016/j.ehj.2003.08.003
Copyright © 2003 by the European Society of Cardiology.
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Editorial

The importance of cholesterol, blood pressure and smoking for coronary heart disease

S Lewington*

University of Oxford, Clinical Trial Service Unit, Oxford 0X2 6HE, UK

* Corresponding author. Tel.: +44-1-8659-404824
E-mail address: sarah.lewington@ctsu.ox.ac.uk

Received 31 July 2003; accepted 22 August 2003

The first 10% of the full text of this article appears below.

See doi:10.1016/S1095-668X(03)00471-8 for the article to which this editorial refers

Worldwide cardiovascular diseases account for half of all deaths in middle age (and considerable additional disability) and one third of all deaths in old age. Most of these deaths involve ischaemic heart disease (IHD) or stroke. Epidemiological studies carried out over the last half century have shown that cigarette smoking, elevated blood pressure and dyslipidaemia increase the risk of cardiovascular diseases and randomized trials have shown that lowering blood pressure and cholesterol prevents cardiovascular disease. Nevertheless, there are popular misconceptions about the relative importance of these classical risk factors, including the widely . . . [Full Text of this Article]


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Related articles in EHJ:

Re-assessing the contribution of serum total cholesterol, blood pressure and cigarette smoking to the aetiology of coronary heart disease: impact of regression dilution bias
Jonathan R Emberson, Peter H Whincup, Richard W Morris, and Mary Walker
EHJ 2003 24: 1719-1726. [Abstract] [FREE Full Text]  



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