Copyright © 2003 by the European Society of Cardiology.
Editorial
Pulmonary arterial hypertension and the vasoconstrictive factor: is there still a role for vasodilator testing?
a National Heart & Lung Institute and Section on Clinical Pharmacology, Imperial College London, London, UK
b Hammersmith Hospital, Du Cane Road, London W12 0HS, UK
Received October 8, 2002;
accepted October 9, 2002
* Corresponding author. Department of Cardiology, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK. Tel.: +44-208-383-2330; fax: +44-208-383-2331
s.gibbs@ic.ac.uk
| The first 10% of the full text of this article appears below. |
See doi:10.1016/S1095-668X(02)00302-0for the article to which this editorial refers.
Recent years have witnessed a transformation in the treatments available for patients with pulmonary arterial hypertension with the development of new therapies that offer significant therapeutic benefit. While the inspiration behind them may have been based on tipping a perceived imbalance in vasoconstrictorvasodilator activity towardsvasodilation, it is emerging that the main action of these new treatments is to prevent (and possibly reverse) pulmonary vascular remodelling. Should this insight change our protocol for investigating and working up
![]()
CiteULike
Connotea
Del.icio.us What's this?
Related articles in EHJ:
- Assessment of the vasodilator response in primary pulmonary hypertension: Comparing prostacyclin and iloprost administered by either infusion or inhalation
- C.F Opitz, R Wensel, M Bettmann, R Schaffarczyk, M Linscheid, R Hetzer, and R Ewert
EHJ 2003 24: 356-365.[Abstract] [FREE Full Text]
This article has been cited by other articles:
![]() |
G. W Mikhail, S. K Prasad, W. Li, P. Rogers, A. H Chester, S. Bayne, D. Stephens, M. Khan, J.S.R Gibbs, T. W Evans, et al. Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mid-term effects Eur. Heart J., March 1, 2004; 25(5): 431 - 436. [Abstract] [Full Text] [PDF] |
||||
