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European Heart Journal 2004 25(3):185-187; doi:10.1016/j.ehj.2003.12.010
Copyright © 2004 by the European Society of Cardiology.
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Editorial

Aortic stenosis: even mild disease is significant

Catherine M. Otto*

Division of Cardiology, University of Washington, Seattle, USA

* Correspondence to: Catherine M. Otto, MD, Professor of Medicine, Director, Cardiology Fellowship Training Programs, Division of Cardiology, Box 356422, University of Washington, Seattle, WA 98195, USA. Tel: +1 206-685-1397; Fax: +1 206-616-4847
E-mail address: cmotto@u.washington.edu

Received 2 December 2003; accepted 4 December 2003

The first 10% of the full text of this article appears below.

See doi:10.1016/j.ehj.2003.12.002for the article to which this editorial refers

The spectrum of calcific aortic valve disease ranges from aortic sclerosis, without obstruction to ventricular outflow, to severe aortic stenosis. The natural history of symptomatic and asymptomatic severe aortic valve stenosis has been evaluated by Doppler echocardiography in several retrospective and prospective studies. In addition, there is substantial data on the rate of haemodynamic progression of aortic stenosis of all degrees of severity. However, there is much less data on clinical outcomes in adults with asymptomatic mild-moderate stenosis.1–3Knowledge of the expected outcomes with mild aortic valve disease is especially important given that aortic sclerosis is present in about 25% of adults over age 65 years and progression to aortic stenosis occurs within 7 years in 16% of patients with aortic sclerosis.4

. . . [Full Text of this Article]

0.1. Progression of aortic stenosis

0.2. Sudden death and left ventricular dysfunction

0.3. Clinical outcome

0.4. Practical applications


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