European Heart Journal Advance Access originally published online on April 19, 2005
European Heart Journal 2005 26(15):1482-1487; doi:10.1093/eurheartj/ehi261
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Accuracy of MSCT coronary angiography with 64-slice technology: first experience
1Department of Medical Radiology, Institute of Diagnostic Radiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland
2Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland
Received 17 December 2004; revised 7 March 2005; accepted 15 March 2005; online publish-ahead-of-print 19 April 2005.
* Corresponding author. Tel: +41 1 255 3662; fax: +41 1 255 4443. E-mail address: simon.wildermuth{at}usz.ch
See page 1451 for the editorial comment on this article (doi:10.1093/eurheartj/ehi322)
Aims The aim of our study was to investigate the accuracy of 64-slice computed tomography (CT) for assessing haemodynamically significant stenoses of coronary arteries.
Methods and results CT angiography was performed in 67 patients (50 male, 17 female; mean age 60.1±10.5 years) with suspected coronary artery disease and compared with invasive coronary angiography. All vessels 
1.5 mm were considered for the assessment of significant coronary artery stenosis (diameter reduction >50%). Forty-seven patients were identified as having significant coronary stenoses on invasive angiography with 18% (176/1005) affected segments. None of the coronary segments needed to be excluded from analysis. CT correctly identified all 20 patients having no significant stenosis on invasive angiography. Overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%.
Conclusion Sixty-four-slice CT provides a high diagnostic accuracy in assessing coronary artery stenoses.
Key Words: Computed tomography • Conventional coronary angiography • Coronary artery disease
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