European Heart Journal Advance Access originally published online on April 19, 2005
European Heart Journal 2005 26(15):1482-1487; doi:10.1093/eurheartj/ehi261
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Accuracy of MSCT coronary angiography with 64-slice technology: first experience
1Department of Medical Radiology, Institute of Diagnostic Radiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland
2Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland
Received 17 December 2004; revised 7 March 2005; accepted 15 March 2005; online publish-ahead-of-print 19 April 2005.
* Corresponding author. Tel: +41 1 255 3662; fax: +41 1 255 4443. E-mail address: simon.wildermuth{at}usz.ch
See page 1451 for the editorial comment on this article (doi:10.1093/eurheartj/ehi322)
Aims The aim of our study was to investigate the accuracy of 64-slice computed tomography (CT) for assessing haemodynamically significant stenoses of coronary arteries.
Methods and results CT angiography was performed in 67 patients (50 male, 17 female; mean age 60.1±10.5 years) with suspected coronary artery disease and compared with invasive coronary angiography. All vessels 
1.5 mm were considered for the assessment of significant coronary artery stenosis (diameter reduction >50%). Forty-seven patients were identified as having significant coronary stenoses on invasive angiography with 18% (176/1005) affected segments. None of the coronary segments needed to be excluded from analysis. CT correctly identified all 20 patients having no significant stenosis on invasive angiography. Overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%.
Conclusion Sixty-four-slice CT provides a high diagnostic accuracy in assessing coronary artery stenoses.
Key Words: Computed tomography • Conventional coronary angiography • Coronary artery disease
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EHJ 2005 26: 1451-1453.[Extract] [FREE Full Text]
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L. Husmann, I. Valenta, O. Gaemperli, O. Adda, V. Treyer, C. A. Wyss, P. Veit-Haibach, F. Tatsugami, G. K. von Schulthess, and P. A. Kaufmann Feasibility of low-dose coronary CT angiography: first experience with prospective ECG-gating Eur. Heart J., January 2, 2008; 29(2): 191 - 197. [Abstract] [Full Text] [PDF]
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J. Hausleiter, T. Meyer, M. Hadamitzky, M. Zankl, P. Gerein, K. Dorrler, A. Kastrati, S. Martinoff, and A. Schomig Non-invasive coronary computed tomographic angiography for patients with suspected coronary artery disease: the Coronary Angiography by Computed Tomography with the Use of a Submillimeter resolution (CACTUS) trial Eur. Heart J., December 2, 2007; 28(24): 3034 - 3041. [Abstract] [Full Text] [PDF]
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J. Abdulla, S. Z. Abildstrom, O. Gotzsche, E. Christensen, L. Kober, and C. Torp-Pedersen 64-multislice detector computed tomography coronary angiography as potential alternative to conventional coronary angiography: a systematic review and meta-analysis Eur. Heart J., December 2, 2007; 28(24): 3042 - 3050. [Abstract] [Full Text] [PDF]
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A. R. Simon, H. Baraki, J. Weidemann, W. Harringer, M. Galanski, and A. Haverich High-resolution 64-slice helical-computer-assisted-tomographical-angiography as a diagnostic tool before CABG surgery: the dawn of a new era? Eur. J. Cardiothorac. Surg., December 1, 2007; 32(6): 896 - 901. [Abstract] [Full Text] [PDF]
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C. S. White and D. Kuo Chest Pain in the Emergency Department: Role of Multidetector CT Radiology, December 1, 2007; 245(3): 672 - 681. [Abstract] [Full Text] [PDF]
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F. Saremi, A. Abolhoda, O. Ashikyan, J. C. Milliken, J. Narula, S. V. Gurudevan, K. Kaushal, and A. Raney Arterial Supply to Sinuatrial and Atrioventricular Nodes: Imaging with Multidetector CT Radiology, December 1, 2007; 246(1): 99 - 107. [Abstract] [Full Text] [PDF]
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M. Hamon, R. Morello, J. W. Riddell, and M. Hamon Coronary Arteries: Diagnostic Performance of 16- versus 64-Section Spiral CT Compared with Invasive Coronary Angiography Meta-Analysis Radiology, December 1, 2007; 245(3): 720 - 731. [Abstract] [Full Text] [PDF]
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H. Brodoefel, U. Kramer, A. Reimann, C. Burgstahler, S. Schroeder, A. Kopp, and M. Heuschmid Dual-Source CT with Improved Temporal Resolution in Assessment of Left Ventricular Function: A Pilot Study Am. J. Roentgenol., November 1, 2007; 189(5): 1064 - 1070. [Abstract] [Full Text] [PDF]
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W. B Meijboom, N. R Mollet, C. A Van Mieghem, A. C Weustink, F. Pugliese, N. van Pelt, F. Cademartiri, E. Vourvouri, P. de Jaegere, G. P Krestin, et al. 64-Slice CT coronary angiography in patients with non-ST elevation acute coronary syndrome Heart, November 1, 2007; 93(11): 1386 - 1392. [Abstract] [Full Text] [PDF]
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L. Husmann, S. Leschka, L. Desbiolles, T. Schepis, O. Gaemperli, B. Seifert, P. Cattin, T. Frauenfelder, T. G. Flohr, B. Marincek, et al. Coronary Artery Motion and Cardiac Phases: Dependency on Heart Rate Implications for CT Image Reconstruction Radiology, November 1, 2007; 245(2): 567 - 576. [Abstract] [Full Text] [PDF]
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W. B. Meijboom, C. A.G. van Mieghem, N. R. Mollet, F. Pugliese, A. C. Weustink, N. van Pelt, F. Cademartiri, K. Nieman, E. Boersma, P. de Jaegere, et al. 64-Slice Computed Tomography Coronary Angiography in Patients With High, Intermediate, or Low Pretest Probability of Significant Coronary Artery Disease J. Am. Coll. Cardiol., October 9, 2007; 50(15): 1469 - 1475. [Abstract] [Full Text] [PDF]
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M. Dewey, H.-P. Dubel, T. Schink, G. Baumann, and B. Hamm Head-to-head comparison of multislice computed tomography and exercise electrocardiography for diagnosis of coronary artery disease Eur. Heart J., October 2, 2007; 28(20): 2485 - 2490. [Abstract] [Full Text] [PDF]
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A. W. Leber, T. Johnson, A. Becker, F. von Ziegler, J. Tittus, K. Nikolaou, M. Reiser, G. Steinbeck, C. R. Becker, and A. Knez Diagnostic accuracy of dual-source multi-slice CT-coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease Eur. Heart J., October 1, 2007; 28(19): 2354 - 2360. [Abstract] [Full Text] [PDF]
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H. Alkadhi, L. Desbiolles, L. Husmann, A. Plass, S. Leschka, H. Scheffel, R. Vachenauer, T. Schepis, O. Gaemperli, T. G. Flohr, et al. Aortic Regurgitation: Assessment with 64-Section CT Radiology, October 1, 2007; 245(1): 111 - 121. [Abstract] [Full Text] [PDF]
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D. Matt, H. Scheffel, S. Leschka, T. G. Flohr, B. Marincek, P. A. Kaufmann, and H. Alkadhi Dual-Source CT Coronary Angiography: Image Quality, Mean Heart Rate, and Heart Rate Variability Am. J. Roentgenol., September 1, 2007; 189(3): 567 - 573. [Abstract] [Full Text] [PDF]
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