Skip Navigation


European Heart Journal Advance Access originally published online on April 28, 2005
European Heart Journal 2005 26(15):1488-1493; doi:10.1093/eurheartj/ehi288
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
26/15/1488    most recent
ehi288v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in EHJ
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (6)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Aoki, J.
Right arrow Articles by Serruys, P. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Aoki, J.
Right arrow Articles by Serruys, P. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Five year clinical effect of coronary stenting and coronary artery bypass grafting in renal insufficient patients with multivessel coronary artery disease: insights from ARTS trial

Jiro Aoki1, Andrew T.L. Ong1, Angela Hoye1, Lex A. van Herwerden1, J. Eduardo Sousa2, Adib Jatene3, Johannes J.R.M. Bonnier4, Jacques P.M.A. Schönberger4, Nigel Buller5, Robert Bonser5, Wietze Lindeboom6, Felix Unger7 and Patrick W. Serruys1,*

1Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
2Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil
3Hospital do Coracao, Sao Paulo, Brazil
4Catharina Ziekenhuis, Eindhoven, The Netherlands
5The Queen Elisabeth Hospital, Birmingham, UK
6Cardialysis, Rotterdam, The Netherlands
7University Klinik für Herzchirurgie, Salzburg, Austria

Received 2 November 2004; revised 20 February 2005; accepted 24 March 2005; online publish-ahead-of-print 28 April 2005.

* Corresponding author. Tel: +31 10 4635269; fax: +31 10 4639154. E-mail address: p.w.j.c.serruys{at}erasmusmc.nl

See page 1456 for the editorial comment on this article (doi:10.1093/eurheartj/ehi332)

Aims To compare coronary stent implantation and bypass surgery for multivessel coronary disease in patients with renal insufficiency.

Methods and results In the ARTS trial, 142 moderate renal insufficient patients (Ccr<60 mL/min) with multivessel coronary disease were randomly assigned to stent implantation (n=69) or CABG (n=73). At 5 years, there was no significant difference between the two groups in terms of mortality (14.5% in the stent group vs. 12.3% in the CABG group, P=0.81), or combined endpoint of death, cerebrovascular accident (CVA), or myocardial infarction (MI) (30.4% in the stent group vs. 23.3% in the CABG group, P=0.35). Among patients who survived without CVA or MI, 18.8% in the stent group underwent a second revascularization procedure when compared with 8.2% in the surgery group (P=0.08). The event-free survival at 5 years was 50.7% in the stent group and 68.5% in the surgery group (P=0.04).

Conclusion At 5 years, the differences in mortality and combined incidence of death, CVA, and MI between coronary stenting and surgery did not reach statistically significant level. However, the occurrence of MACCE in the stent group was higher than in the CABG group, mainly driven by the higher incidence of repeat revascularization in the stent group.

Key Words: Stent • Coronary artery bypass • Renal insufficiency


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in EHJ:

Revascularization in patients with chronic kidney disease: the state of the ARTS
Bertram Pitt
EHJ 2005 26: 1456-1457. [Extract] [Full Text]  



This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
J.F. M. Bechtel, C. Detter, T. Fischlein, T. Krabatsch, B. R. Osswald, F.-C. Riess, F. Scholz, M. Schonburg, C. Stamm, H.-H. Sievers, et al.
Cardiac Surgery in Patients on Dialysis: Decreased 30-Day Mortality, Unchanged Overall Survival
Ann. Thorac. Surg., January 1, 2008; 85(1): 147 - 153.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
D. M. Bravata, A. L. Gienger, K. M. McDonald, V. Sundaram, M. V. Perez, R. Varghese, J. R. Kapoor, R. Ardehali, D. K. Owens, and M. A. Hlatky
Systematic Review: The Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Graft Surgery
Ann Intern Med, November 20, 2007; 147(10): 703 - 716.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. M. Holzhey, S. Jacobs, M. Mochalski, T. Walther, H. Thiele, F. W. Mohr, and V. Falk
Seven-Year Follow-up After Minimally Invasive Direct Coronary Artery Bypass: Experience With More Than 1300 Patients
Ann. Thorac. Surg., January 1, 2007; 83(1): 108 - 114.
[Abstract] [Full Text] [PDF]

Home page
 QJMHome page
N.C. Edwards, R.P. Steeds, C.J. Ferro, and J.N. Townend
The treatment of coronary artery disease in patients with chronic kidney disease
QJM, November 1, 2006; 99(11): 723 - 736.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
B. Pitt
Revascularization in patients with chronic kidney disease: the state of the ARTS
Eur. Heart J., August 1, 2005; 26(15): 1456 - 1457.
[Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.