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European Heart Journal Advance Access originally published online on March 8, 2005
European Heart Journal 2005 26(7):637-638; doi:10.1093/eurheartj/ehi234
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Heart rate, regularity, and synchronicity in heart failure: a tale of three brothers

Christoph Stellbrink*

Medizinische Klinik I der RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, Germany

* Corresponding author. Tel: +49 241 8089945; fax: +49 241 8082303. E-mail address: cstellbrink@ukaachen.de

This editorial refers to ‘Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy’{dagger} by V. Melenovsky et al., on page 705, and ‘Comparative assessment of right, left and biventricular pacing in patients with permanent atrial fibrillation’{ddagger} by M. Brignole et al., on page 712

The first 10% of the full text of this article appears below.

The electrical consequences of heart failure and their impact on disease progression have frequently been underestimated. It is long known that a significant per cent of heart failure patients develop disease of the conduction system and atrial fibrillation (AF). Conduction disturbances are not only a marker of disease progression but may lead to further haemodynamic deterioration, thus representing another vicious circle in the heart failure syndrome. It has also been recognized that AF may impair haemodynamics by the loss of atrial contribution to stroke volume, by reducing filling time especially if the ventricular response to AF is uncontrolled and by rate irregularity itself.1 In fact, AF with rapid ventricular conduction may ultimately lead to left ventricular (LV) . . . [Full Text of this Article]


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Related articles in EHJ:

Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy
Vojtech Melenovsky, Ilan Hay, Barry J. Fetics, Barry A. Borlaug, Andrew Kramer, Joseph M. Pastore, Ronald Berger, and David A. Kass
EHJ 2005 26: 705-711. [Abstract] [FREE Full Text]  

Comparative assessment of right, left, and biventricular pacing in patients with permanent atrial fibrillation
M. Brignole, M. Gammage, E. Puggioni, P. Alboni, A. Raviele, R. Sutton, P. Vardas, M.G. Bongiorni, L. Bergfeldt, C. Menozzi, G. Musso, and on behalf of the Optimal Pacing SITE Study Investigators
EHJ 2005 26: 712-722. [Abstract] [FREE Full Text]