Skip Navigation


European Heart Journal Advance Access originally published online on April 7, 2006
European Heart Journal 2006 27(10):1207-1215; doi:10.1093/eurheartj/ehi845
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
27/10/1207    most recent
ehi845v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (42)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Tavazzi, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tavazzi, L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Nationwide survey on acute heart failure in cardiology ward services in Italy

Luigi Tavazzi1,*, Aldo P. Maggioni2, Donata Lucci2, Giuseppe Cacciatore3, Gerardo Ansalone4, Fabrizio Oliva5, Maurizio Porcu6 on behalf of the Italian survey on Acute Heart Failure Investigators

1 Department of Cardiology, IRCCS Policlinico S. Matteo, Piazzale Golgi, 2-27100 Pavia, Italy
2 ANMCO Research Center, Florence, Italy
3 Department of Cardiology, Ospedale S. Giovanni Addolorata, Rome, Italy
4 Department of Cardiology, Ospedale Madre Giuseppina Vannini, Rome, Italy
5 Department of Cardiology, Ospedale Niguarda, Milan, Italy
6 Department of Cardiology, Ospedale S. Michele Brotzu, Cagliari, Italy

Received 28 March 2005; revised 23 February 2006; accepted 9 March 2006; online publish-ahead-of-print 7 April 2006.

* Corresponding author. Tel: +39 0 55 5001703; fax: +39 0 55 583400.E-mail address: centro_studi{at}anmco.it

Aims Chronic heart failure (HF) is recognized as an important public health problem but little attention has been focused on acute-stage HF.

Methods and results Nationwide, prospective, observational study setting 206 cardiology centres with intensive cardiac care units. During 3 months, 2807 patients diagnosed as having de novo acute HF (44%) or worsening chronic HF (56%) were enrolled. Acute pulmonary oedema was the presenting clinical feature in 49.6% of patients, cardiogenic shock in 7.7%, and worsened NYHA functional class in 42.7% of cases. Anaemia (Hb<12 g/dL) was present in 46% of patients, renal dysfunction (creatinine ≥1.5 mg%) in 47%, and hyponatraemia (≤136 mEq/L) in 45%. An ejection fraction (EF)>40% was found in 34% of cases. Intravenous diuretics, nitrates, and inotropes were given to 95, 51, and 25% of patients, respectively. The median duration of hospital stay was 9 days. In-hospital mortality rate was 7.3%. Older age, use of inotropic drugs, elevated troponin, hyponatraemia, anaemia, and elevated blood urea nitrogen were independent predictors of all-cause death; prior revascularization procedures and elevated blood pressure were indicators of a better outcome. The rehospitalization rate within 6 months was 38.1%, all-cause mortality from discharge to 6 months was 12.8%.

Conclusion Acute HF is an ominous condition, needing more research activity and resources.

Key Words: Heart failure • Acute heart failure • Survey • Observational research • Inotropes • Nitrates


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Qual Saf Health CareHome page
M Panella, S Marchisio, M L Demarchi, L Manzoli, and F Di Stanislao
Reduced in-hospital mortality for heart failure with clinical pathways: the results of a cluster randomised controlled trial
Qual. Saf. Health Care, October 1, 2009; 18(5): 369 - 373.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
V. Tibaldi, G. Isaia, C. Scarafiotti, F. Gariglio, M. Zanocchi, M. Bo, S. Bergerone, and N. A. Ricauda
Hospital at Home for Elderly Patients With Acute Decompensation of Chronic Heart Failure: A Prospective Randomized Controlled Trial
Arch Intern Med, September 28, 2009; 169(17): 1569 - 1575.
[Abstract] [Full Text] [PDF]

Home page
 EuropaceHome page
R. P. Ricci, A. Quesada, J. Almendral, F. Arribas, C. Wolpert, P. Adragao, M. Zoni-Berisso, X. Navarro, T. DeSanto, A. Grammatico, et al.
Dual-chamber implantable cardioverter defibrillators reduce clinical adverse events related to atrial fibrillation when compared with single-chamber defibrillators: a subanalysis of the DATAS trial
Europace, May 1, 2009; 11(5): 587 - 593.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart Fail SupplHome page
M. Komajda
How well are we implementing evidence-based care?
Eur J Heart Fail Suppl, April 1, 2009; 8(suppl_1): i39 - i44.
[Full Text] [PDF]

Home page
 Eur J Heart FailHome page
N. M. Hawkins, M. C. Petrie, P. S. Jhund, G. W. Chalmers, F. G. Dunn, and J. J.V. McMurray
Heart failure and chronic obstructive pulmonary disease: diagnostic pitfalls and epidemiology
Eur J Heart Fail, February 1, 2009; 11(2): 130 - 139.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. D. Flaherty, J. J. Bax, L. De Luca, J. S. Rossi, C. J. Davidson, G. Filippatos, P. P. Liu, M. A. Konstam, B. Greenberg, M. R. Mehra, et al.
Acute heart failure syndromes in patients with coronary artery disease early assessment and treatment.
J. Am. Coll. Cardiol., January 20, 2009; 53(3): 254 - 263.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
F. Orso, S. Baldasseroni, G. Fabbri, L. Gonzini, D. Lucci, C. D'Ambrosi, M. Gobbi, G. Lecchi, S. Randazzo, G. Masotti, et al.
Role of beta-blockers in patients admitted for worsening heart failure in a real world setting: data from the Italian Survey on Acute Heart Failure
Eur J Heart Fail, January 1, 2009; 11(1): 77 - 84.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. E.A. Blair, F. Zannad, M. A. Konstam, T. Cook, B. Traver, J. C. Burnett Jr, L. Grinfeld, H. Krasa, A. P. Maggioni, C. Orlandi, et al.
Continental Differences in Clinical Characteristics, Management, and Outcomes in Patients Hospitalized With Worsening Heart Failure: Results From the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Program
J. Am. Coll. Cardiol., November 11, 2008; 52(20): 1640 - 1648.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
Authors/Task Force Members, K. Dickstein, A. Cohen-Solal, G. Filippatos, J. J.V. McMurray, P. Ponikowski, P. A. Poole-Wilson, A. Stromberg, D. J. van Veldhuisen, D. Atar, et al.
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
Eur. Heart J., October 1, 2008; 29(19): 2388 - 2442.
[Full Text] [PDF]

Home page
 Eur J Heart FailHome page
K. Dickstein, A. Cohen-Solal, G. Filippatos, J. J.V. McMurray, P. Ponikowski, P. A. Poole-Wilson, A. Stromberg, D. J. van Veldhuisen, D. Atar, A. W. Hoes, et al.
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
Eur J Heart Fail, October 1, 2008; 10(10): 933 - 989.
[Full Text] [PDF]

Home page
 Cardiovasc ResHome page
S. Grote-Wessels, H. A. Baba, P. Boknik, A. El-Armouche, L. Fabritz, H.-J. Gillmann, D. Kucerova, M. Matus, F. U. Muller, J. Neumann, et al.
Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload
Cardiovasc Res, August 1, 2008; 79(3): 464 - 471.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
J. S. Ross, G. K. Mulvey, B. Stauffer, V. Patlolla, S. M. Bernheim, P. S. Keenan, and H. M. Krumholz
Statistical Models and Patient Predictors of Readmission for Heart Failure: A Systematic Review
Arch Intern Med, July 14, 2008; 168(13): 1371 - 1386.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
A. Gray, S. Goodacre, D. E. Newby, M. Masson, F. Sampson, J. Nicholl, and the 3CPO Trialists
Noninvasive Ventilation in Acute Cardiogenic Pulmonary Edema
N. Engl. J. Med., July 10, 2008; 359(2): 142 - 151.
[Abstract] [Full Text] [PDF]

Home page
 Mayo Clin Proc.Home page
J. P. Dal-Bianco, A. S. Jaffe, M. R. Bell, and J. K. Oh
Cardiac Function and Brain-Type Natriuretic Peptide in First-Time Flash Pulmonary Edema
Mayo Clin. Proc., March 1, 2008; 83(3): 289 - 296.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
F. Zannad, W. G. Stough, B. Pitt, J. G.F. Cleland, K. F. Adams, N. L. Geller, C. Torp-Pedersen, B.-A. Kirwan, and F. Follath
Heart failure as an endpoint in heart failure and non-heart failure cardiovascular clinical trials: the need for a consensus definition
Eur. Heart J., February 1, 2008; 29(3): 413 - 421.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
M. Metra, S. Nodari, G. Parrinello, T. Bordonali, S. Bugatti, R. Danesi, B. Fontanella, C. Lombardi, P. Milani, G. Verzura, et al.
Worsening renal function in patients hospitalised for acute heart failure: Clinical implications and prognostic significance
Eur J Heart Fail, February 1, 2008; 10(2): 188 - 195.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
C. Adamopoulos, F. Zannad, R. Fay, A. Mebazaa, A. Cohen-Solal, L. Guize, Y. Juilliere, and F. Alla
Ejection fraction and blood pressure are important and interactive predictors of 4-week mortality in severe acute heart failure
Eur J Heart Fail, September 1, 2007; 9(9): 935 - 941.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
J. Lassus, V.-P. Harjola, R. Sund, K. Siirila-Waris, J. Melin, K. Peuhkurinen, K. Pulkki, M. S. Nieminen, and for the FINN-AKVA Study group
Prognostic value of cystatin C in acute heart failure in relation to other markers of renal function and NT-proBNP
Eur. Heart J., August 1, 2007; 28(15): 1841 - 1847.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
M. Metra, P. Ponikowski, K. Dickstein, J. J.V. McMurray, A. Gavazzi, C.-H. Bergh, A. G. Fraser, T. Jaarsma, A. Pitsis, P. Mohacsi, et al.
Advanced chronic heart failure: A position statement from the Study Group on Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology
Eur J Heart Fail, June 1, 2007; 9(6-7): 684 - 694.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
R.B. Singh, F. DeMeester, L. Juneja, V. Michirova, and D. Pella
New risk factors of heart failure?
Eur. Heart J., April 2, 2007; 28(8): 1038 - 1039.
[Full Text] [PDF]

Home page
 JAMAHome page
M. A. Konstam, M. Gheorghiade, J. C. Burnett Jr, L. Grinfeld, A. P. Maggioni, K. Swedberg, J. E. Udelson, F. Zannad, T. Cook, J. Ouyang, et al.
Effects of Oral Tolvaptan in Patients Hospitalized for Worsening Heart Failure: The EVEREST Outcome Trial
JAMA, March 28, 2007; 297(12): 1319 - 1331.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
M. Gheorghiade, M. A. Konstam, J. C. Burnett Jr, L. Grinfeld, A. P. Maggioni, K. Swedberg, J. E. Udelson, F. Zannad, T. Cook, J. Ouyang, et al.
Short-term Clinical Effects of Tolvaptan, an Oral Vasopressin Antagonist, in Patients Hospitalized for Heart Failure: The EVEREST Clinical Status Trials
JAMA, March 28, 2007; 297(12): 1332 - 1343.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
K. Siirila-Waris, J. Lassus, J. Melin, K. Peuhkurinen, M. S. Nieminen, V.-P. Harjola, and for the FINN-AKVA study group
Characteristics, outcomes, and predictors of 1-year mortality in patients hospitalized for acute heart failure
Eur. Heart J., December 2, 2006; 27(24): 3011 - 3017.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
M. S. Nieminen, D. Brutsaert, K. Dickstein, H. Drexler, F. Follath, V.-P. Harjola, M. Hochadel, M. Komajda, J. Lassus, J. L. Lopez-Sendon, et al.
EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population
Eur. Heart J., November 2, 2006; 27(22): 2725 - 2736.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.