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European Heart Journal Advance Access originally published online on June 8, 2006
European Heart Journal 2006 27(13):1511-1512; doi:10.1093/eurheartj/ehl107
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

WEST: new data on the integration of early thrombolysis and mechanical intervention in the early management of STEMI

Philippe Gabriel Steg1,* and Nicolas Danchin2

1 Centre Hospitalier Bichat-Claude Bernard, 4-rue Henri Huchard, AP-HP, 75018 Paris, France
2 Hôpital Européen Georges Pompidou, AP-HP, Paris, France

* Corresponding author. Tel: +33 1 40 25 86 69; fax: +33 1 40 25 88 65. E-mail address: gabriel.steg@bch.aphp.fr

This editorial refers to ‘A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) Study’{dagger} by WEST Steering Committee, on page 1530

The first 10% of the full text of this article appears below.

The choice between reperfusion strategies to manage ST-segment elevation acute myocardial infarction is a topic of immense interest, given the frequency of STEMI, its short-term mortality, and the potential impact on organization of acute cardiac care. There is general agreement that primary PCI, performed in timely fashion in an experienced centre, is an excellent and probably the best strategy.1 However, in many regions of the world, this cannot be implemented. Therefore, intravenous thrombolysis remains the default strategy. Several studies have therefore explored two avenues to improve the results of intravenous thrombolysis: the first is to attempt to provide earlier treatment by using pre-hospital thrombolysis (PHT). In general, PHT is associated with a . . . [Full Text of this Article]


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Related articles in EHJ:

A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) study
Paul W. Armstrong and WEST Steering Committee
EHJ 2006 27: 1530-1538. [Abstract] [Full Text]