European Heart Journal Advance Access originally published online on July 21, 2006
European Heart Journal 2006 27(16):1889-1890; doi:10.1093/eurheartj/ehl126
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IVUS-VH: a predictor of plaque morphology?
CVPath, International Registry of Pathology, 19 Firstfield Road, Gaithersburg, MD 20878, USA
* Corresponding author. Tel: +1 301 208 2490; fax: +1 301 208 3745. E-mail address: rvirmani@cvpath.org
This editorial refers to Global characterization of coronary plaque rupture phenotype using three-vessel intravascular ultrasound radiofrequency data analysis
by G.A. Rodriguez-Granillo et al., on page 1921
| The first 150 words of the full text of this article appear below. |
Imaging modalities that identify plaques vulnerable to rupture offer the possibility of preventing the most common substrate of coronary thrombosis. The incidence of progression of thin-cap atheroma, as identified at PCI, is largely unknown. Glaser et al.1 have demonstrated that at 1-year follow-up of a cohort of patients undergoing PCI, at least 6% develop progression of disease requiring additional PCI for another target lesion. The major predictors of plaque progression were multivessel disease, prior PCI, and age less than 65 years. Goldstein et al.2 demonstrated that 17% of acute MI patients with multiple complex angiographic lesions undergo PCI of non-culprit lesions within 1 year. These data underscore the need for identifying those plaques in high-risk patients who will benefit from prophylactic intervention. The hope is that newer imaging modalities, such as IVUS-virtual histology (VH) will precisely identify those lesions.
Rodriguez-Granillo et al.3 describe IVUS-VH in a prospective study of 40
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Related articles in EHJ:
- Global characterization of coronary plaque rupture phenotype using three-vessel intravascular ultrasound radiofrequency data analysis
- Gastón A. Rodriguez-Granillo, Héctor M. García-García, Marco Valgimigli, Sophia Vaina, Carlos van Mieghem, Robert J. van Geuns, Maarten van der Ent, Evelyn Regar, Peter de Jaegere, Willem van der Giessen, Pim de Feyter, and Patrick W. Serruys
EHJ 2006 27: 1921-1927.[Abstract] [FREE Full Text]
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S. K. Mehta, J. R. McCrary, A. D. Frutkin, W. J.S. Dolla, and S. P. Marso Intravascular ultrasound radiofrequency analysis of coronary atherosclerosis: an emerging technology for the assessment of vulnerable plaque Eur. Heart J., June 1, 2007; 28(11): 1283 - 1288. [Abstract] [Full Text] [PDF] |
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