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European Heart Journal Advance Access originally published online on October 11, 2006
European Heart Journal 2006 27(21):2497-2498; doi:10.1093/eurheartj/ehl312
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Arterial stiffness: reflections on the arterial pulse

Michael F. O'Rourke1,* and Stanley S. Franklin2

1 Suite 810, St. Vincent's Clinic/University of New South Wales/VCCRI, 438 Victoria Street, Darlinghurst, NSW 2010, Sydney, Australia
2 University of California, Irvine, California, USA

* Corresponding author. Tel: +61 2 8382 6874; fax: +61 2 8382 6875. E-mail address: M.ORourke@unsw.edu.au

This editorial refers to ‘Expert consensus document on arterial stiffness: methodological issues and clinical applications’{dagger} by S. Laurent et al., on page 2588

The first 150 words of the full text of this article appear below.

Arteriosclerosis—arterial stiffening—is the basic cause of isolated systolic hypertension (ISH) and the present epidemic of heart failure in the elderly.1 Arteriosclerosis is equally important for the development of coronary events, stroke, dementia, and renal failure. The underlying pathology was described by Osler2 as ‘senile arteriosclerosis’ to distinguish it from essential hypertension (Osler's ‘diffuse arteriosclerosis’) and ‘nodular arteriosclerosis’ that is now described as atherosclerosis. Although we usually identify the precursor as ISH, the measurement of blood pressure by cuff sphygmomanometer is only a surrogate of the underlying disease3 and an unsatisfactory method for detecting its early presence and progress. Recognizing this, the European Societies of Cardiology and of Hypertension (ESC and ESH, respectively) established guidelines for the management of arterial hypertension, and drew attention to methods for measuring arterial stiffness as pulse wave velocity or analysing the pulse waveform, which may identify the arterial target organ damage at an early stage.4

. . . [Full Text of this Article]


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Related articles in EHJ:

Expert consensus document on arterial stiffness: methodological issues and clinical applications
Stephane Laurent, John Cockcroft, Luc Van Bortel, Pierre Boutouyrie, Cristina Giannattasio, Daniel Hayoz, Bruno Pannier, Charalambos Vlachopoulos, Ian Wilkinson, Harry Struijker-Boudier, and on behalf of the European Network for Non-invasive Investigation of Large Arteries
EHJ 2006 27: 2588-2605. [Abstract] [FREE Full Text]