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European Heart Journal Advance Access originally published online on November 25, 2005
European Heart Journal 2006 27(3):258-259; doi:10.1093/eurheartj/ehi671
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Percutaneous PFO closure, further data but many unanswered questions

John D.R. Thomson*

Department of Congenital Heart Disease, E Floor, Jubilee Wing, Leeds General Infirmary, Great George Street, Leeds, UK

* Corresponding author. Tel: +44 113 3928184; fax: +44 113 3928375. E-mail address: john.thomson@lineone.net

This editorial refers to ‘Patent foramen ovale closure in patients with cryptogenic thrombo-embolic events using the Cardia PFO occluder’{dagger} by C. Spies et al., on page 365

The first 10% of the full text of this article appears below.

The pace of technological development in interventional congenital cardiology over the last two decades has been fast and relentless. Successful and reliable closure of secundum atrial septal defects in the catheter laboratory translated to interest in the use of similar devices for the occlusion of the patent foramen ovale (PFO), a common remnant of the fetal circulation. The pathological potential of the PFO in the genesis of unexplained thrombotic stroke had long been suspected,1 with Lechat et al.2 in 1988 reporting a higher prevalence of PFO in patients with cryptogenic thrombotic stroke, an observation confirmed in a number of subsequent studies.3 With low . . . [Full Text of this Article]


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Related articles in EHJ:

Patent foramen ovale closure in patients with cryptogenic thrombo-embolic events using the Cardia PFO occluder
Christian Spies, Roland Strasheim, Ines Timmermanns, and Rainer Schraeder
EHJ 2006 27: 365-371. [Abstract] [Full Text]