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European Heart Journal Advance Access originally published online on November 11, 2005
European Heart Journal 2006 27(3):296-301; doi:10.1093/eurheartj/ehi630
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© The European Society of Cardiology 2005. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Coronary heart disease: from a disease of middle-aged men in the late 1970s to a disease of elderly women in the 2000s

Anna Kattainen1,*, Veikko Salomaa2, Tommi Härkänen1, Antti Jula1, Risto Kaaja3, Y. Antero Kesäniemi4, Mika Kähönen5, Leena Moilanen6, Markku S. Nieminen7, Arpo Aromaa1 and Antti Reunanen1

1Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, FI-00300 Helsinki, Finland
2Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
3Department of Obstetrics and Gynaecology, University Central Hospital, Helsinki, Finland
4Department of Internal Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland
5Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland
6Department of Medicine, Kuopio University Hospital, Kuopio, Finland
7Division of Cardiology, University Central Hospital, Helsinki, Finland

Received 13 June 2005; revised 6 October 2005; accepted 13 October 2005; online publish-ahead-of-print 11 November 2005.

* Corresponding author. Tel: +358 9 4744 8716; fax: +358 9 4744 8760. E-mail address: anna.kattainen{at}ktl.fi

Aims To analyse secular changes in the prevalence of coronary heart disease (CHD) and to assess changes in the burden of CHD at population level.

Methods and results Data were used from two large cross-sectional health examination surveys representing the entire Finnish adult population in 1980 and 2000. In the 1978–80 survey, the sample covered 5101 individuals aged ≥45, of whom 88% participated. The 2000–2001 survey comprised 5310 individuals in the same age range. Participation rate in the health examination was 87%. Prevalence of CHD decreased in men and women under the age of 65 and increased among those aged ≥75. Prevalence of large Q-waves indicating previous myocardial infarction decreased in all male age groups and in women aged 65–74. The total estimated number of persons with CHD increased by 18% (95% CI=6–30) during the past 20 years in Finland. In 1980, the most dominant CHD group was men aged 45–64, whereas in 2000, women aged ≥75 comprised the largest CHD group.

Conclusion Although the prevalence of CHD has decreased among middle-aged persons, the number of CHD cases has increased during the past 20 years in Finland.

Key Words: Coronary disease • Angina • Myocardial infarction • Sex • Epidemiology


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