European Heart Journal Advance Access originally published online on May 3, 2007
European Heart Journal 2007 28(14):1782-1783; doi:10.1093/eurheartj/ehm139
© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: observations from the ESTEEM trial
Institute of Cardiology
John Radcliffe Hospital
Oxford
UK
Policlinico Gemelli
Institute of Cardiology
Catholic University
Rome 00168
Italy
Institute of Cardiology
John Radcliffe Hospital
Oxford
UK
Division of Cardiology
University of Turin
Turin
Italy
Department of Medicine
Virginia Commonwealth University
Richmond
VA, USA
Institute of Cardiology
Catholic University
Rome 00168
Italy
Antwerp Cardiovascular Institute Middelheim
AZ Middelheim
Antwerp Belgium
Tel: +44 1865 228934 Fax: +44 1865 220585 E-mail address: luctes@gmail.com
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We have carefully read the interesting article of Christersson et al.1 focusing on the pivotal issue of risk stratification and prognosis in patients recovering from an acute myocardial infarction (AMI). Analysing data from a cohort of patients enrolled in the ESTEEM trial, the authors aimed at evaluating whether markers for thrombin generation, fibrin turnover, and activated thromboplastin time (APTT) were related to clinical outcomes and whether change in the level of these markers could predict the risk of new ischaemic events