Skip Navigation


European Heart Journal Advance Access originally published online on February 15, 2007
European Heart Journal 2007 28(16):1993-2000; doi:10.1093/eurheartj/ehl550
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
28/16/1993    most recent
ehl550v2
ehl550v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Klieverik, L. M.A.
Right arrow Articles by Bogers, A. J.J.C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Klieverik, L. M.A.
Right arrow Articles by Bogers, A. J.J.C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

The Ross operation: a Trojan horse?{dagger}

Loes M.A. Klieverik1,*, Johanna J.M. Takkenberg1, Jos A. Bekkers1, Jolien W. Roos-Hesselink2, Maarten Witsenburg3 and Ad J.J.C. Bogers1

1 Department of Cardio-Thoracic Surgery, Erasmus University Medical Center, Bd 571, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
2 Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
3 Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands

Received 6 October 2006; revised 22 December 2006; accepted 25 January 2007; online publish-ahead-of-print 15 February 2007.

* Corresponding author. Tel: +31 10 463 4481; fax: +31 10 463 3993. E-mail address: l.klieverik{at}erasmusmc.nl

Aims: The Ross operation is the operation of choice for children who require aortic valve replacement (AVR) and may also provide a good option in selected adult patients. Although the autograft does not require anticoagulation and has a superior haemodynamic profile, concern regarding autograft and allograft longevity has risen. In this light, we report the 13-year results of our prospective autograft cohort study.

Methods and results: Between 1988 and 2005, 146 consecutive patients underwent AVR with a pulmonary autograft at Erasmus Medical Center Rotterdam. Mean age was 22 years (SD 13; range 4 months–52 years), 66% were male. Hospital mortality was 2.7% (N = 4); during follow-up four more patients died. Thirteen-year survival was 94 ± 2%. Over time, 22 patients required autograft reoperation for progressive neo-aortic root dilatation. In addition, eight patients required allograft reoperation. Freedom from autograft reoperation at 13 years was 69 ± 7%. Freedom from allograft reoperation for structural failure at 13 years was 87 ± 5%. Risk factors for autograft reoperation were previous AVR and adult patient age.

Conclusion: Although survival of the Rotterdam autograft cohort is excellent, over time a worrisome increase in reoperation rate is observed. Given the progressive autograft dilatation, careful follow-up of these patients is warranted in the second decade after operation.

Key Words: Ross operation • Prospective study • Survival • Autograft dilatation • Reoperation

{dagger} Presented at the World Congress of Cardiology in Barcelona, Spain, on 4 September 2006.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.