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European Heart Journal Advance Access originally published online on January 5, 2007
European Heart Journal 2007 28(2):146-147; doi:10.1093/eurheartj/ehl433
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Heart-type fatty acid-binding proteins (H-FABP): a reliable tool for initial risk stratification of pulmonary embolism?

Bertrand Renaud* and Alfred Ngako

Department of Emergency Medicine, Centre Hospitalier Universitaire Henri Mondor (AP-HP), Créteil, France

* Corresponding author. Tel: +33 1 49 81 25 23; fax: +33 1 49 81 29 87. E-mail address: bertrand.renaud@hmn.aphp.fr

This editorial refers to ‘Heart-type fatty acid-binding protein permits early risk stratification of pulmonary embolism’{dagger} by M. Puls et al., on page 224

The first 10% of the full text of this article appears below.

The severity of pulmonary embolism (PE) ranges from asymptomatic to cardiogenic shock with corresponding short-term mortality between 2 and 95%. Whereas the former could be discharged early or managed entirely as outpatients using low-molecular-weight heparin, those with greater severity of PE require rapid echocardiography to evaluate for indications for immediate thrombolysis or embolectomy.2,3 However, most patients with PE fall between these two extremes. Patients with PE who do not initially present with life-threatening criteria are usually admitted to a hospital ward where those with intermediate risk might experience a life-threatening recurrent episode requiring emergent thrombolysis and critical care. Therefore, among patients with intermediate clinical severity, it is critical to accurately identify those at risk for adverse medical outcome.

Despite recent advances in risk stratification, . . . [Full Text of this Article]


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Related articles in EHJ:

Heart-type fatty acid-binding protein permits early risk stratification of pulmonary embolism
Miriam Puls, Claudia Dellas, Mareike Lankeit, Manfred Olschewski, Lutz Binder, Anette Geibel, Christian Reiner, Katrin Schäfer, Gerd Hasenfuss, and Stavros Konstantinides
EHJ 2007 28: 224-229. [Abstract] [FREE Full Text]