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European Heart Journal Advance Access originally published online on February 13, 2007
European Heart Journal 2007 28(5):531-532; doi:10.1093/eurheartj/ehl514
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Ruminating on OAT: is the case closed?

Paul W. Armstrong*

2-51 Medical Sciences Building, University of Alberta Edmonton, Alberta, T6G 2H7 Canada

Received 14 November 2006; revised 9 January 2007; accepted 12 January 2007; online publish-ahead-of-print 13 February 2007.

* Corresponding author. Tel: +1 780 492 0591; fax: +1 780 492 9486. E-mail address: paul.armstrong@ualberta.ca

The first 10% of the full text of this article appears below.

Occlusion of an epicardial coronary artery is a well recognized pathophysiological substrate for acute ST-elevation myocardial infarction (MI). Whether and how coronary patency is restored after this event is markedly variable among patients. Unquestionably, coronary reperfusion enhances clinical outcomes and can occur spontaneously or through pharmacological or mechanical methods.1 Moreover, if the culprit coronary artery associated with MI is open prior to an attempt at mechanical coronary intervention, a better long-term clinical outcome results.2

Since the long-term outlook for patients recovering from MI appears enhanced when the culprit coronary artery is patent, enthusiasm for . . . [Full Text of this Article]


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