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European Heart Journal Advance Access originally published online on December 21, 2007
European Heart Journal 2008 29(2):150-152; doi:10.1093/eurheartj/ehm535
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Peripheral arterial disease enters the biomarker era. Does risk stratification tell us something that we don't already know?

Heather L. Gornik*

Department of CV Medicine, Cleveland Clinic, 9500 Euclid Avenue–Desk S60, Cleveland, OH 44195, USA

* Corresponding author. Tel: +1 216 445 3689, Fax: +1 216 444 7370, Email: gornikh@ccf.org

This editorial refers to ‘Myeloperoxidase, but not C-reactive protein, predicts cardiovascular risk in peripheral arterial disease’ by G. Brevetti et al., on page 224

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{dagger} doi:10.1093/eurheartj/ehm587 Back

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

After decades of obscurity, peripheral arterial disease (PAD) is gaining recognition as a serious cardiovascular (CV) disorder. It is estimated that >27 million individuals in Europe and the USA have PAD, though there remains a widespread lack of awareness of this disorder among at-risk patients and healthcare professionals.1,2 In addition to functional impairment and related effects on quality of life, individuals with PAD are at a markedly increased risk of a major CV event, namely myocardial infarction (MI), stroke, and death.

Brevetti and colleagues have investigated the utility of two inflammatory biomarkers, high sensitivity C-reactive protein (hs-CRP) and . . . [Full Text of this Article]


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Related articles in EHJ:

Myeloperoxidase, but not C-reactive protein, predicts cardiovascular risk in peripheral arterial disease
Gregorio Brevetti, Vittorio Schiano, Eugenio Laurenzano, Giuseppe Giugliano, Mario Petretta, Francesco Scopacasa, and Massimo Chiariello
EHJ 2008 29: 224-230. [Abstract] [FREE Full Text]