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European Heart Journal Advance Access originally published online on October 21, 2008
European Heart Journal 2008 29(22):2710-2712; doi:10.1093/eurheartj/ehn468
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Effect of isoflavone supplement on endothelial function: does efficacy vary with atherosclerotic burden?

Hiroki Teragawa1,*, Yukihito Higashi2 and Yasuki Kihara1

1 Department of Cardiovascular Medicine
2 Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan

* Corresponding author. Tel: +81 82 257 5540, Fax: +81 82 257 5554, Email: hteraga@hiroshima-u.ac.jp

This editorial refers to ‘Reduction of C-reactive protein with isoflavone supplement reverses endothelial dysfunction in patients with ischaemic stroke’{dagger} by Y.-H. Chan et al., on page 2800

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

Endothelial dysfunction is widely considered as a prognostic marker of future cardiovascular events in clinical settings, even in patients who do not have untoward symptoms of cardiovascular disease.1 Thus, treatments aimed at restoring endothelial dysfunction have important implications Many studies have demonstrated that supplementary treatments can improve endothelial function.2 These favourable effects may be due to improved abnormal nitric oxide metabolism, mediated by mechanisms such as antioxidant or anti-inflammatory effects.

Isoflavones are . . . [Full Text of this Article]


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Related articles in EHJ:

Reduction of C-reactive protein with isoflavone supplement reverses endothelial dysfunction in patients with ischaemic stroke
Yap-Hang Chan, Kui-Kai Lau, Kai-Hang Yiu, Sheung-Wai Li, Hiu-Ting Chan, Daniel Yee-Tak Fong, Sidney Tam, Chu-Pak Lau, and Hung-Fat Tse
EHJ 2008 29: 2800-2807. [Abstract] [FREE Full Text]