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European Heart Journal Advance Access originally published online on April 7, 2008
European Heart Journal 2008 29(9):1084-1085; doi:10.1093/eurheartj/ehn051
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Evaluating the impact of atrial dilatation on atrial calcium cycling

David R. Van Wagoner*

Department of Molecular Cardiology, NE-61, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195 USA

* Corresponding author. Email: vanwagd@ccf.org

This editorial refers to ‘Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation’{dagger} by S. Dinanian et al., on page 1190

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

With increased longevity, the prevalence of ageing-related diseases is increasing. Atrial fibrillation (AF) is one of the age-related conditions that is approaching epidemic proportions. AF is an important cause of cardioembolic stroke, and the primary cause of cardioembolic stroke in the elderly population. Thrombus formation is in part attributed to the greatly impaired atrial contractility during AF. As in the ventricle, atrial contractility is dependent on the excitation–contraction coupling process in which . . . [Full Text of this Article]


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Related articles in EHJ:

Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation
Sylvie Dinanian, Christophe Boixel, Christophe Juin, Jean-Sébastien Hulot, Alain Coulombe, Catherine Rücker-Martin, Nicolas Bonnet, Bruno Le Grand, Michel Slama, Jean-Jacques Mercadier, and Stéphane N. Hatem
EHJ 2008 29: 1190-1197. [Abstract] [Full Text]