European Heart Journal Advance Access originally published online on June 1, 2009
European Heart Journal 2009 30(13):1549-1550; doi:10.1093/eurheartj/ehp216
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org
Myocardial bridging and sudden death in hypertrophic cardiomyopathy: Salome drops another veil
1 Referral Center for Myocardial Diseases, Heart and Vessel Department, Careggi University Hospital, Florence, Italy
2 Heart Science Centre, Imperial College London, Harefield, UK
* Corresponding author. Tel: +39 055 7945138, Fax: +39 055 7949335; Email: olivottoi@aou-careggi.toscana.it
This editorial refers to Myocardial bridging, a frequent component of the hypertrophic cardiomyopathy phenotype, lacks systematic association with sudden cardiac death
, by C. Basso et al., on page 1627
| The first 10% of the full text of this article appears below. |
Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease at the clinical, phenotypic, and molecular level.1 In spite of considerable progress in understanding the disease, many issues continue to be shrouded in mystery, with very slow and often incomplete shedding of the veils, reminiscent of Salome's dance. These issues include the unpredictable occurrence of sudden cardiac death, the clinical relevance of coronary artery bridging, and their possible relationship.1–6
To this day, HCM is among the most common causes of sudden cardiac death in the young, and strategies aimed at improving risk stratification remain less than satisfactory, largely due to the capricious course and individual heterogeneity of the disease.7 Several potential predictors of risk have been identified, each with very low positive predictive accuracy, that may be important in some patients but have
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- Myocardial bridging, a frequent component of the hypertrophic cardiomyopathy phenotype, lacks systematic association with sudden cardiac death
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EHJ 2009 30: 1627-1634.[Abstract] [Full Text]